Human protein-based biomaterials in preclinical modelling

Nature Reviews Bioengineering. 2026;4(5):399-400. doi: 10.1038/s44222-026-00425-7

Human protein-based biomaterials facilitate the development of preclinical models that integrate predictive value and ethical responsibility. Metatissue uses decellularized extracellular matrix from placenta samples and human blood to create tunable, xeno-free substrates for 3D cell culture, minimizing the reliance on animal models and accelerating translational research.

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