@article{bibcite_8941, keywords = {Biomaterials {\textendash} proteins, Drug development, Drug screening, Tissue engineering, translational research}, author = {Mariana Dias and Catarina A. Cust{\'o}dio and Jo{\~a}o F. Mano}, title = {Human protein-based biomaterials in preclinical modelling}, abstract = {Human protein-based biomaterials facilitate the development of preclinical models that integrate predictive value and ethical responsibility. Metatissue uses decellularized extracellular matrix from placenta samples and human blood to create tunable, xeno-free substrates for 3D cell culture, minimizing the reliance on animal models and accelerating translational research.}, year = {2026}, journal = {Nature Reviews Bioengineering}, volume = {4}, pages = {399-400}, month = {2026-05}, issn = {2731-6092}, url = {https://www.nature.com/articles/s44222-026-00425-7}, doi = {10.1038/s44222-026-00425-7}, language = {en}, }