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How Should Treatment of Animals Beyond the Lab Factor Into Institutional Review?
ReferenceLaurie Sellars , Jeff Sebo AMA Journal of Ethics. 2024;26(9):716-723. doi: 10.1001/amajethics.2024.716 Discussions of nonhuman research ethics tend to focus on what we owe nonhuman research subjects in laboratory settings only. But humans make critical …
The Application of Organs-on-a-Chip in Dental, Oral, and Craniofacial Research
ReferenceC. Huang , F. Sanaei , W.P.R. Verdurmen , F. Yang , W. Ji , X. F. Walboomers Journal of Dental Research. 2023;102(4):364-375. doi: 10.1177/00220345221145555 The current development of microfluidics-based microphysiological systems (MPSs) will rapidly lead …
Training the Next Generation of Researchers in the Organ-on-Chip Field
ReferenceAlessia Moruzzi , Tanvi Shroff , Silke Keller , Peter Loskill , Madalena Cipriano Education Sciences. 2023;13(2):144. doi: 10.3390/educsci13020144 Organ-on-chip (OoC) technology bridges the principles of biology and engineering to create a new generation …
Tumor organoid biobank-new platform for medical research
ReferenceXuexue Xie , Xinyu Li , Wei Song Scientific Reports. 2023;13(1):1819. doi: 10.1038/s41598-023-29065-2 Organoids are a new type of 3D model for tumor research, which makes up for the shortcomings of cell lines and xenograft models, and promotes the …
The commitment of the human cell atlas to humanity
ReferenceIdo Amit , Kristin Ardlie , Fabiana Arzuaga , Gordon Awandare , Gary Bader , Alexander Bernier , Piero Carninci , Stacey Donnelly , Roland Eils , Alistair R. R. Forrest , Henry T. Greely , Roderic Guigo , Nir Hacohen , Muzlifah Haniffa , Emily Sarah Kirby …
Monocytes and T cells incorporated in full skin equivalents to study innate or adaptive immune reactions after burn injury
ReferencePatrick P. G. Mulder , Marcel Vlig , Anouk Elgersma , Lotte Rozemeijer , Leonore S. Mastenbroek , Esther Middelkoop , Irma Joosten , Hans J. P. M. Koenen , Bouke K. H. L. Boekema Frontiers in Immunology. 2023;14. doi: 10.3389/fimmu.2023.1264716 …
A comprehensive battery of flow cytometric immunoassays for the in vitro testing of chemical effects in human blood cells
ReferenceArkadiusz Pierzchalski , Ana C. Zenclussen , Gunda Herberth Frontiers in Immunology. 2024;14. doi: 10.3389/fimmu.2023.1327960 BackgroundThere is a growing need for immunological assays to test toxic and modulatory effects of …
Integration: Gospel for immune bioinformatician on epitope-based therapy
ReferenceBaozeng Sun , Junqi Zhang , Zhikui Li , Mingyang Xie , Cheng Luo , Yongkai Wang , Longyu Chen , Yueyue Wang , Dongbo Jiang , Kun Yang Frontiers in Immunology. 2023;14. doi: 10.3389/fimmu.2023.1075419 1 IntroductionPeptide-based vaccines are attracting …
Mathematical modeling in autoimmune diseases: from theory to clinical application
ReferenceYaroslav Ugolkov , Antonina Nikitich , Cristina Leon , Gabriel Helmlinger , Kirill Peskov , Victor Sokolov , Alina Volkova Frontiers in Immunology. 2024;15. doi: 10.3389/fimmu.2024.1371620 The research & development (R&D) of novel therapeutic …
A novel IgE epitope-specific antibodies-based sandwich ELISA for sensitive measurement of immunoreactivity changes of peanut allergen Ara h 2 in processed foods
ReferenceYan Yan , Liming Li , Caiyun Long , Yaping Dong , Jinyu Li , Caiyi Shen , Yiqian Zhao , Jiangqiang Zhao , Jianbin Wang , Anqi Xiong , Xin Li , Hongbing Chen , Shengfa He Frontiers in Nutrition. 2024;11. doi: 10.3389/fnut.2024.1323553 …