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Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration
ReferenceXin Cui , Xinwei Li , Huimin Zheng , Yun Su , Shuyu Zhang , Mengjie Li , Xiaoyan Hao , Shuo Zhang , Zhengwei Hu , Zongping Xia , Changhe Shi , Yuming Xu , Chengyuan Mao npj Parkinson's Disease. 2024;10(1):1-14. doi: 10.1038/s41531-024-00799-8 Parkinson’s …
Dynamic interface printing
ReferenceCallum Vidler , Michael Halwes , Kirill Kolesnik , Philipp Segeritz , Matthew Mail , Anders J. Barlow , Emmanuelle M. Koehl , Anand Ramakrishnan , Lilith M. Caballero Aguilar , David R. Nisbet , Daniel J. Scott , Daniel E. Heath , Kenneth B. Crozier , …
Cryopreservation of in vitro human tissue models
ReferenceYaqi Sheng , Yan Yan Shery Huang Nature Reviews Bioengineering. 2024:1-3. doi: 10.1038/s44222-024-00261-7 The widespread use and translation of engineered in vitro tissues, such as organoids, organ-on-chip devices and microphysiological models, will …
High-throughput Bronchus-on-a-Chip system for modeling the human bronchus
ReferenceAkina Mori , Marjolein Vermeer , Lenie J. van den Broek , Jeroen Heijmans , Arnaud Nicolas , Josse Bouwhuis , Todd Burton , Kazushi Matsumura , Kazuhiro Ohashi , Shigeaki Ito , Bart Kramer Scientific Reports. 2024;14(1):26248. doi: …
In vivo imaging of the human brain with the Iseult 11.7-T MRI scanner
ReferenceNicolas Boulant , Franck Mauconduit , Vincent Gras , Alexis Amadon , Caroline Le Ster , Michel Luong , Aurélien Massire , Christophe Pallier , Laure Sabatier , Michel Bottlaender , Alexandre Vignaud , Denis Le Bihan Nature Methods. 2024;21(11):2013-2016. …
Human organoids-on-chips for biomedical research and applications
ReferenceHui Wang , Xiufan Ning , Feng Zhao , Hui Zhao , Dong Li Theranostics. 2024;14(2):788. doi: 10.7150/thno.90492 Human organoids-on-chips (OrgOCs) are the synergism of human organoids (HOs) technology and microfluidic organs-on-chips (OOCs). OOCs can mimic …
Advancing alternative methods to reduce animal testing
ReferenceChad P. Nelson , Paul Brown , Suzanne Fitzpatrick , Kevin A. Ford , Paul C. Howard , Tracy MacGill , Edward E. C. Margerrison , Jacqueline O’Shaughnessy , Tucker A. Patterson , Rakesh Raghuwanshi , Rodney Rouse , Selen Stromgren , Kyung E. Sung , Luis G. …
Machine learning model to predict obesity using gut metabolite and brain microstructure data
ReferenceVadim Osadchiy , Roshan Bal , Emeran A. Mayer , Rama Kunapuli , Tien Dong , Priten Vora , Danny Petrasek , Cathy Liu , Jean Stains , Arpana Gupta Scientific Reports. 2023;13(1):5488. doi: 10.1038/s41598-023-32713-2 A growing body of preclinical and …
Advances in gut–brain organ chips
ReferenceYu Zhang , Si-Ming Lu , Jian-Jian Zhuang , Li-Guo Liang Cell Proliferation. 2024;57(9):e13724. doi: 10.1111/cpr.13724 The brain and gut are sensory organs responsible for sensing, transmitting, integrating, and responding to signals from the internal and …
Exploring human pancreatic organoid modelling through single-cell RNA sequencing analysis
ReferenceAlessandro Cherubini , Francesco Rusconi , Roberta Piras , Kaja Nicole Wächtershäuser , Marta Dossena , Mario Barilani , Cecilia Mei , Lotta Hof , Valeria Sordi , Francesco Pampaloni , Vincenza Dolo , Lorenzo Piemonti , Lorenza Lazzari Communications …