microphysiological systems

Katharina Stefanie Nitsche, Iris Müller, Sophie Malcomber, Paul Lawford Carmichael, Hans Bouwmeester. Alternatives to animal-derived extracellular matrix hydrogels? An explorative study with HepaRG cells in animal-free hydrogels under static and dynamic culture conditions. Frontiers in Toxicology. 2025;7. doi:10.3389/ftox.2025.1649393

Aakash Patel, Suruchi Poddar, Daniel Nierenberg, et al. Microphysiological system to address the opioid crisis: A novel multi-organ model of acute opioid overdose and recovery. Current Research in Toxicology. 2025;8:100209. doi:10.1016/j.crtox.2024.100209

Hiroshi Kimura, Masaki Nishikawa, Naokata Kutsuzawa, et al. Advancements in Microphysiological systems: Exploring organoids and organ-on-a-chip technologies in drug development -focus on pharmacokinetics related organs-. Drug Metabolism and Pharmacokinetics. 2025;60:101046. doi:10.1016/j.dmpk.2024.101046

K. Taylor, R. Ram, L. Ewart, et al. Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury. Frontiers in Drug Discovery. 2025;5. doi:10.3389/fddsv.2025.1536756

Kristifor Sunderic, Andrew M. Wright, Nicole Kleinstreuer, et al. Complement-ARIE: Catalyzing the development and adoption of new approach methodologies. NAM Journal. 2025;1:100026. doi:10.1016/j.namjnl.2025.100026

Itzy E. Morales Pantoja, Lixuan Ding, Paulo E. C. Leite, et al. A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems. Advanced Biology. 2024;8(8):2300198. doi:10.1002/adbi.202300198

Seungman Park, Thomas C. Laskow, Jingchun Chen, Prasun Guha, Buddhadeb Dawn, Deok-Ho Kim. Microphysiological systems for human aging research. Aging Cell. 2024;23(3):e14070. doi:10.1111/acel.14070

David Pamies, Jason Ekert, Marie-Gabrielle Zurich, et al. Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility. Stem Cell Reports. 2024;19(5):604-617. doi:10.1016/j.stemcr.2024.03.009

David Pamies, Jason Ekert, Marie-Gabrielle Zurich, et al. Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility. Stem Cell Reports. 2024;19(5):604-617. doi:10.1016/j.stemcr.2024.03.009

Kimberly A. Homan. Industry Adoption of Organoids and Organs-on-Chip Technology: Toward a Paradox of Choice. Advanced Biology. 2023;7(6):2200334. doi:10.1002/adbi.202200334