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Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury

K. Taylor, R. Ram, L. Ewart, C. Goldring, G. Russomanno, G. P. Aithal, T. Kostrzewski, C. Bauch, J. M. Wilkinson, S. Modi, J. G. Kenna, J. Bailey
Frontiers in Drug Discovery. 2025;5. doi: 10.3389/fddsv.2025.1536756
https://www.frontiersin.org/journals/drug-discovery/articles/10.3389/fddsv.2025.1536756/full
Keywords
DILI
animal testing
in vitro methods
liver injury
microphysiological systems
replacement
safety testing
spheroids
Library Collection(s)
Toxicology
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The content of this website is adapted from Krebs et al., Author Guide for Addressing Animal Methods Bias in Publishing. Advanced Science. 2023 Aug 30:e2303226. doi: 10.1002/advs.202303226. © 2023 by Krebs et al. is licensed under CC BY 4.0. Advanced Science, published by Wiley-VCH GmbH. Wiley-VCH GmbH does not endorse the COLAAB, nor our use of the content. 

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