Ethics, policy, and legislation

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Michael J. Fossler, C. Edwin Garner. The FDA Roadmap to Reducing Animal Testing in Preclinical Safety Studies: Where Will It Lead Us? Clinical Pharmacology in Drug Development. 2026;15(3):e70046. doi:10.1002/cpdd.70046
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Federico Germani, Julian W. März, Alessandro Luciani, Olivier Devuyst, Nikola Biller-Andorno. Ethical and legal considerations of digital animal models: pioneering reduction and replacement. Trends in Biotechnology. 2026;44(3):593-595. doi:10.1016/j.tibtech.2025.08.011
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Matthias Eggel, Samuel Camenzind, Paulin Jirkof. Reasons to Reduce Surplus Animals in Research (in Switzerland) – Or Why the Killing and Death of Animals and Potentially Standard Husbandry Conditions Should be Classified as Harms. LEOH - Journal of Animal Law, Ethics and One Health. 2026:1-15. doi:10.58590/leoh.2026.001
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Donald E. Ingber. Challenges and opportunities for human Organ Chips in FDA assessments and pharma pipelines,. Cell Stem Cell. 2026. doi:10.1016/j.stem.2025.12.022
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Kristof Dhont, Gordon Hodson. Speciesism and the psychology of animal exploitation. Nature Reviews Psychology. 2026:1-15. doi:10.1038/s44159-026-00585-8
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Jill Monnissen, Andreas De Block. Exploring ethical reasoning and welfare perceptions of Octopus vulgaris paralarvae among scientific and non-scientific communities. Laboratory Animals. 2026:00236772261441121. doi:10.1177/00236772261441121
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Benjamin Victor Ineichen. We need less animal research, better animal research, and animal research done for the right reasons. Journal of Translational Medicine. 2026. doi:10.1186/s12967-026-08259-y
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Yining Du, Yuan Fang, Shiwei Ni. Overcoming Paradigm Inertia: Publishing Incentives and Peer Review Bias as the True Rate-Limiting Steps in Reducing Animal Research. Journal of Translational Medicine. 2026;24(1):818. doi:10.1186/s12967-026-08526-y
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Elliott Johnson, Howard Reed, Anna Thew, Matthew Johnson. Non-animal new approach methodologies (NAMs): Increasingly effective in validated contexts, more ethical and more economically productive. NAM Journal. 2026;2:100102. doi:10.1016/j.namjnl.2026.100102
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Thomas Hartung. The turning point: April 2025 marks historic shift in US animal testing policy. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2504301
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