Ethics, policy, and legislation

Victor J. Krawczyk. Moral shocks to invoke compassion: depicting the suffering and death of animals in animal research and testing facilities. Journal of Aesthetics & Culture. 2025;17(1):2579371. doi:10.1080/20004214.2025.2579371

Fred Schwaller. A mental-health crisis plagues PhDs — these evidence-led initiatives offer help. Nature. 2025. doi:10.1038/d41586-025-01083-2

Ricardo Scheufen Tieghi, Tracy Beth Høeg, Martin A. Makary, Nicole Kleinstreuer. The Promise of Animal Testing Alternatives at the U.S. Food and Drug Administration and National Institutes of Health. NEJM AI. 2025;3(1):AIpc2500587. doi:10.1056/AIpc2500587

Jennifer Bell, Vanessa Zaiatz Bittencourt. Dealing with animal death and writing about it: Cultivating resilience in biotechnology writing. Medical Writing. 2025;34(1):70-73. https://journal.emwa.org/rare-diseases/biotechnology/.

Laurence Walder, Giorgia Pallocca, Luísa F. Bastos, et al. EU roadmap for phasing out animal testing for chemical safety assessments: Recommendations from a multi-stakeholder roundtable. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2503241

Thomas Hartung. The turning point: April 2025 marks historic shift in US animal testing policy. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2504301

Francesca Pistollato, Fabia Furtmann, Annalisa Gastaldello, et al. Bridging the prevention gap: funding distribution and methodological shifts in prevention-focused biomedical research under EU framework programmes. Journal of Translational Medicine. 2025;23(1):1006. doi:10.1186/s12967-025-07019-8

Sarah A Carratt, Christina L Zuch de Zafra, Elias Oziolor, et al. An industry perspective on the FDA Modernization Act 2.0/3.0: potential next steps for sponsors to reduce animal use in drug development. Toxicological Sciences. 2025;203(1):28-34. doi:10.1093/toxsci/kfae122

John J. Pippin, Jarrod Bailey, Mark Kennedy, et al. Institutional animal care and use committees and the challenges of evaluating animal research proposals. Research Integrity and Peer Review. 2025;10(1):11. doi:10.1186/s41073-025-00169-9

Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025;24(6):401-402. doi:10.1038/d41573-025-00038-6