Ethics, policy, and legislation

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Bob Fischer, Meghan Barrett, Brendan Parent, Alexandra K. Schnell, Jeff Sebo. Ethical guidance for invertebrate research. Biology Direct. 2026. doi:10.1186/s13062-026-00963-5
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Parissa Barai, Vaishnavi Pogakula, Jagnoor Singh Sandhu, Amrita Parida, Nandakumar Krishnadas, Gollapalle Lakshminarayanashastry Viswanatha. Re‐evaluating the forced swim test: ethical, scientific, and regulatory drivers for validated alternatives. Frontiers in Animal Science. 2026;7. doi:10.3389/fanim.2026.1692092
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Michael J. Fossler, C. Edwin Garner. The FDA Roadmap to Reducing Animal Testing in Preclinical Safety Studies: Where Will It Lead Us? Clinical Pharmacology in Drug Development. 2026;15(3):e70046. doi:10.1002/cpdd.70046
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Yanning Hao, Tyna Dao, Nakissa Sadrieh. Applications of in vitro new approach methodologies (NAMs) in drug development: A scoping analysis of titles of nonclinical study reports submitted to the FDA. Regulatory Toxicology and Pharmacology. 2026;172:106246. doi:10.1016/j.yrtph.2026.106246
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Nico Dario Müller. No transition without participation: Why moving beyond animal studies requires public input into the research agenda. Politics and the Life Sciences. 2026:1-15. doi:10.1017/pls.2026.10023
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Jia Yao, Jackye Peretz, Ilona Bebenek, et al. FDA/CDER/OND Experience With New Approach Methodologies (NAMs). International journal of toxicology. 2026;45(2):136-156. doi:10.1177/10915818251384270
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Christian Rodriguez, Charlotte E. Blattner, Angela K. Martin. How ignoring the harm of killing undermines the ethical legitimacy of animal research: a case study from Switzerland. Medicine, Health Care and Philosophy. 2026. doi:10.1007/s11019-026-10382-y
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Jill Monnissen, Andreas De Block. Exploring ethical reasoning and welfare perceptions of Octopus vulgaris paralarvae among scientific and non-scientific communities. Laboratory Animals. 2026:00236772261441121. doi:10.1177/00236772261441121
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kathrynlm. Should patients have a say in the authorisation of animal experiments? https://blogs.bmj.com/medical-ethics/2026/08/06/should-patients-have-a-say-in-the-authorisation-of-animal-experiments/. Published 2026.
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Tyna Dao, Nakissa Sadrieh. A CDER perspective: Landscape of New Approach Methodologies (NAMs) submitted in drug development programs. Regulatory toxicology and pharmacology: RTP. 2026;165:106007. doi:10.1016/j.yrtph.2025.106007
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