Ethics, policy, and legislation

Angela Bearth, Nicolas Roth, Tom Jansen, et al. New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use. Environment International. 2025;196:109279. doi:10.1016/j.envint.2025.109279

Jean Knight, Costanza Rovida, Kate Willett, Jay Ingram. Fish count, too – The animal toll of REACH aquatic toxicity tests. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2506011

Francesca Pistollato, Gregor Burkhart, Pierre Deceuninck, et al. What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate. Frontiers in Public Health. 2024;12:1417684. doi:10.3389/fpubh.2024.1417684

Natalie Anderson, Rachel Smith. Rethinking the Three Rs: Growing Momentum Toward a New Gold Standard in Australian Research. Alternatives to Laboratory Animals. 2024;52(4):224-231. doi:10.1177/02611929241259117

Patricia Frías-Álvarez, Gustavo Ortiz-Millán. Use of animals for scientific and educational purposes by Mexican institutions. Gaceta Médica de México. 2024;160(2):212-220. https://www.gacetamedicademexico.com/frame_eng.php?id=935.

Jarrod Bailey. It’s Time to Review the Three Rs, to Make them More Fit for Purpose in the 21st Century. Alternatives to Laboratory Animals. 2024;52(3):155-165. doi:10.1177/02611929241241187

Kevin Vezirian, Laurent Bègue, Brock Bastian. Mindless furry test-tubes: Categorizing animals as lab-subjects leads to their mind denial. Journal of Experimental Social Psychology. 2024;114:104629. doi:10.1016/j.jesp.2024.104629

Michael Balls, Rolf Bass, Rodger Curren, et al. 60 Years of the 3Rs symposium: Lessons learned and the road ahead. Alternatives to Animal Experimentation. 2024;41(2):179-201. doi:10.14573/altex.2403061

Helder Constantino, Francesca Pistollato, Troy Seidle. Transitioning biomedical research toward human-centric methodologies: systems-based strategies. Drug Discovery Today. 2024;29(4):103947. doi:10.1016/j.drudis.2024.103947

Amanda M. Lindkvist, Lina Koppel, Gustav Tinghög. Bounded research ethicality: researchers rate themselves and their field as better than others at following good research practice. Scientific Reports. 2024;14(1):3050. doi:10.1038/s41598-024-53450-0