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Spheroids, organoids and kidneys-on-chips: how complex human cellular models have assisted in the study of kidney disease and renal ciliopathies
ReferenceRebecca Marie Dewhurst , Elisa Molinari , John A. Sayer Microfluidics and Nanofluidics. 2023;27(3):21. doi: 10.1007/s10404-023-02629-4 Kidney disease is one of the leading causes of morbidity worldwide, emphasizing the importance for physiologically …
Better Science, Fewer Animals: Catalyzing NIH Grant Making to Improve Biomedical Research and Meet Societal Goals
ReferenceMikalah Singer , Paul Locke Animal Law Review. 2023;29(1):65-101. Animal models are currently the “gold standard” in biomedical research. However, new approaches that do not involve the use of nonhuman animals are evolving to address the public health and …
Distrust in grant peer review—reasons and remedies
ReferenceLiv Langfeldt , Ingvild Reymert , Silje Marie Svartefoss Science and Public Policy. 2023;51(1):28-41. doi: 10.1093/scipol/scad051 With the increasing reliance on competitive grants to fund research, we see a review system under pressure. While peer review …
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development
ReferenceRobert Jordan , Stephanie L Ford-Scheimer , Rodolfo M Alarcon , Anthony Atala , Jeffrey T Borenstein , Kyle R Brimacombe , Sara Cherry , Hans Clevers , Mindy I Davis , Simon G P Funnell , Lee Gehrke , Linda G Griffith , Abigail C Grossman , Thomas Hartung …
A database of human predictive patch test data for skin sensitization
ReferenceJudy Strickland , Jaleh Abedini , David G. Allen , John Gordon , Victoria Hull , Nicole C. Kleinstreuer , Hon-Sum Ko , Joanna Matheson , Hermann-Josef Thierse , James Truax , Jens T. Vanselow , Matthias Herzler Archives of Toxicology. …
Making Reviewers Visible: Openness, Accountability, and Credit
ReferenceFiona Godlee JAMA. 2002;287(21):2762-2765. doi: 10.1001/jama.287.21.2762 Anonymity for peer reviewers remains the overwhelming norm within biomedical journals. While acknowledging that open review is not without challenges, this article presents 4 key …
Translating Scientific Discovery Into Health Policy Impact: Innovative Bibliometrics Bridge Translational Research Publications to Policy Literature
ReferenceNicole M. Llewellyn , Amber A. Weber , Clara M. Pelfrey , Deborah DiazGranados , Eric J. Nehl Academic Medicine. ;98(8):896. doi: 10.1097/ACM.0000000000005225 To understand how translational science efforts lead to outcomes, it is common to examine …
The impact of antidepressants on human neurodevelopment: Brain organoids as experimental tools
ReferenceLuciana Simões Rafagnin Marinho , Gabrielly Maria Denadai Chiarantin , Juliane Midori Ikebara , Débora Sterzeck Cardoso , Théo Henrique de Lima-Vasconcellos , Guilherme Shigueto Vilar Higa , Mariana Sacrini Ayres Ferraz , Roberto De Pasquale , Silvia …
Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage
ReferenceFoluwasomi A. Oyefeso , Alysson R. Muotri , Christopher G. Wilson , Michael J. Pecaut Developmental Neurobiology. 2021;81(5):653-670. doi: 10.1002/dneu.22828 Oxidative stress (OS) is one of the most significant propagators of systemic damage with …
What is a cell type?
ReferenceJonas Simon Fleck , J. Gray Camp , Barbara Treutlein Science. 2023;381(6659):733-734. doi: 10.1126/science.adf6162 https://www.science.org/doi/10.1126/science.adf6162 Library Collection(s) Reviews and perspectives Download Citation BibTeX EndNote X3 XML …