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ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
ReferenceCatarina Martins-Costa , Andrea Wiegers , Vincent A. Pham , Jaydeep Sidhaye , Balint Doleschall , Maria Novatchkova , Thomas Lendl , Marielle Piber , Angela Peer , Paul Möseneder , Marlene Stuempflen , Siu Yu A. Chow , Rainer Seidl , Daniela Prayer , …
A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution
ReferenceAlexander Shapson-Coe , Michał Januszewski , Daniel R. Berger , Art Pope , Yuelong Wu , Tim Blakely , Richard L. Schalek , Peter H. Li , Shuohong Wang , Jeremy Maitin-Shepard , Neha Karlupia , Sven Dorkenwald , Evelina Sjostedt , Laramie Leavitt , Dongil …
Mindless furry test-tubes: Categorizing animals as lab-subjects leads to their mind denial
ReferenceKevin Vezirian , Laurent Bègue , Brock Bastian Journal of Experimental Social Psychology. 2024;114:104629. doi: 10.1016/j.jesp.2024.104629 Despite caring for animals, most people use products tested on lab-animals daily, and rarely consider the …
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma
ReferenceGrégory Seumois , Ciro RamÃrez-Suástegui , Benjamin J. Schmiedel , Shu Liang , Bjoern Peters , Alessandro Sette , Pandurangan Vijayanand Science Immunology. 2020;5(48):eaba6087. doi: 10.1126/sciimmunol.aba6087 CD4+ T helper (TH) cells and regulatory T …
A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma
ReferenceJanna C. Nawroth , Carolina Lucchesi , Deion Cheng , Abhishek Shukla , Justin Ngyuen , Tanvi Shroff , Antonio Varone , Katia Karalis , Hyun-Hee Lee , Stephen Alves , Geraldine A. Hamilton , Michael Salmon , Remi Villenave American Journal of Respiratory …
A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm
ReferenceOnur Kilic , Arum Yoon , Sagar R. Shah , Hwan Mee Yong , Alejandro Ruiz-Valls , Hao Chang , Reynold A. Panettieri , Stephen B. Liggett , Alfredo Quiñones-Hinojosa , Steven S. An , Andre Levchenko Nature Biomedical Engineering. 2019;3:532-544. doi: …
Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells
ReferenceTengku Ibrahim Maulana , Claudia Teufel , Madalena Cipriano , Julia Roosz , Lisa Lazarevski , Francijna E. van den Hil , Lukas Scheller , Valeria Orlova , André Koch , Michael Hudecek , Miriam Alb , Peter Loskill Cell Stem Cell. 2024;31(7):989-1002.e9. …
Novel synthetic clot analogs for in-vitro stroke modelling
ReferenceHelena Guerreiro , Nadine Wortmann , Thomas Andersek , Tuan N. Ngo , Andreas M. Frölich , Dieter Krause , Jens Fiehler , Anna A. Kyselyova , Fabian Flottmann PLOS ONE. ;17(9):e0274211. doi: 10.1371/journal.pone.0274211 Purpose The increased demand for …
Electrochemically induced in vitro focal hypoxia in human neurons
ReferenceJoseph J. Y. Wong , Balazs V. Varga , Ragnhildur Thóra Káradóttir , Elizabeth A. H. Hall Frontiers in Cell and Developmental Biology. 2022;10. doi: 10.3389/fcell.2022.968341 …
Modeling ischemic stroke in a triculture neurovascular unit on-a-chip
ReferenceNienke R. Wevers , Arya Lekshmi Nair , Tania M. Fowke , Maria Pontier , Dhanesh G. Kasi , Xandor M. Spijkers , Charlie Hallard , Gwenaëlle Rabussier , Remko van Vught , Paul Vulto , Helga E. de Vries , Henriëtte L. Lanz Fluids and Barriers of the CNS. …