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Applications of the microphysiology systems database for experimental ADME-Tox and disease models
ReferenceMark Schurdak , Lawrence Vernetti , Luke Bergenthal , Quinn K. Wolter , Tong Ying Shun , Sandra Karcher , D. Lansing Taylor , Albert Gough Lab on a Chip. 2020;20(8):1472-1492. doi: 10.1039/C9LC01047E To accelerate the development and application of …
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
ReferenceYuling Han , Xiaohua Duan , Liuliu Yang , Benjamin E. Nilsson-Payant , Pengfei Wang , Fuyu Duan , Xuming Tang , Tomer M. Yaron , Tuo Zhang , Skyler Uhl , Yaron Bram , Chanel Richardson , Jiajun Zhu , Zeping Zhao , David Redmond , Sean Houghton , Duc-Huy …
Modeling human adaptive immune responses with tonsil organoids
ReferenceLisa E. Wagar , Ameen Salahudeen , Christian M. Constantz , Ben S. Wendel , Michael M. Lyons , Vamsee Mallajosyula , Lauren P. Jatt , Julia Z. Adamska , Lisa K. Blum , Neha Gupta , Katherine J. L. Jackson , Fan Yang , Katharina Röltgen , Krishna M. Roskin …
Infection of bat and human intestinal organoids by SARS-CoV-2
ReferenceJie Zhou , Cun Li , Xiaojuan Liu , Man Chun Chiu , Xiaoyu Zhao , Dong Wang , Yuxuan Wei , Andrew Lee , Anna Jinxia Zhang , Hin Chu , Jian-Piao Cai , Cyril Chik-Yan Yip , Ivy Hau-Yee Chan , Kenneth Kak-Yuen Wong , Owen Tak-Yin Tsang , Kwok-Hung Chan , …
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses
ReferenceJoep Beumer , Maarten H. Geurts , Mart M. Lamers , Jens Puschhof , Jingshu Zhang , Jelte van der Vaart , Anna Z. Mykytyn , Tim I. Breugem , Samra Riesebosch , Debby Schipper , Petra B. van den Doel , Wim de Lau , Cayetano Pleguezuelos-Manzano , Georg …
Coronavirus disease 2019: A tissue engineering and regenerative medicine perspective
ReferenceAbbas Shafiee , Lida Moradi , Mayasari Lim , Jason Brown Stem Cells Translational Medicine. 2021;10(1):27-38. doi: 10.1002/sctm.20-0197 Current therapies for novel coronavirus disease (COVID-19) are generally used to manage rather than cure this highly …
Putting Science into Standards workshop on standards for organ-on-chip
ReferenceMonica Piergiovanni , Ozlem Cangar , Sofia B. Leite , Livia Mian , Andreas Jenet , Raffaella Corvi , Maurice Whelan , Fabio Taucer , Ashok Ganesh Stem Cell Reports. 2021;16(9):2076-2077. doi: 10.1016/j.stemcr.2021.07.010 The European Commission Joint …
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations
ReferenceLouisa Helms , Silvia Marchiano , Ian B. Stanaway , Tien-Ying Hsiang , Benjamin A. Juliar , Shally Saini , Yan Ting Zhao , Akshita Khanna , Rajasree Menon , Fadhl Alakwaa , Carmen Mikacenic , Eric D. Morrell , Mark M. Wurfel , Matthias Kretzler , Jennifer …
Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection
ReferenceArun Sharma , Gustavo Garcia , Yizhou Wang , Jasmine T. Plummer , Kouki Morizono , Vaithilingaraja Arumugaswami , Clive N. Svendsen Cell Reports. Medicine. 2020;1(4):100052. doi: 10.1016/j.xcrm.2020.100052 Coronavirus disease 2019 (COVID-19) is a pandemic …
Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics
ReferenceBérénice Charrez , Verena Charwat , Brian A. Siemons , Ishan Goswami , Courtney Sakolish , Yu-Syuan Luo , Henrik Finsberg , Andrew G. Edwards , Evan W. Miller , Ivan Rusyn , Kevin E. Healy Frontiers in Pharmacology. 2021;12:684252. doi: …