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Toward Good In Vitro Reporting Standards
ReferenceThomas Hartung , Rob De Vries , Sebastian Hoffmann , Helena T. Hogberg , Lena Smirnova , Katya Tsaioun , Paul Whaley , Marcel Leist Alternatives to Animal Experimentation. 2019;36(1):3-17. doi: 10.14573/altex.1812191 A good experiment reported badly is …
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice
ReferenceDongeun Huh , Daniel C. Leslie , Benjamin D. Matthews , Jacob P. Fraser , Samuel Jurek , Geraldine A. Hamilton , Kevin S. Thorneloe , Michael Allen McAlexander , Donald E. Ingber Science Translational Medicine. 2012;4(159). doi: …
Reconstituting Organ-Level Lung Functions on a Chip
ReferenceDongeun Huh , Benjamin D. Matthews , Akiko Mammoto , MartÃn Montoya-Zavala , Hong Yuan Hsin , Donald E. Ingber Science. 2010;328(5986):1662-1668. doi: 10.1126/science.1188302 https://www.science.org/doi/10.1126/science.1188302 Library Collection(s) …
Reproducing human and cross-species drug toxicities using a Liver-Chip
ReferenceKyung-Jin Jang , Monicah A. Otieno , Janey Ronxhi , Heng-Keang Lim , Lorna Ewart , Konstantia R. Kodella , Debora B. Petropolis , Gauri Kulkarni , Jonathan E. Rubins , David Conegliano , Janna Nawroth , Damir Simic , Wing Lam , Monica Singer , Erio Barale …
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
ReferenceMagdalena Kasendra , Alessio Tovaglieri , Alexandra Sontheimer-Phelps , Sasan Jalili-Firoozinezhad , Amir Bein , Angeliki Chalkiadaki , William Scholl , Cheng Zhang , Hannah Rickner , Camilla A. Richmond , Hu Li , David T. Breault , Donald E. Ingber …
Bias in peer review
ReferenceCarole J. Lee , Cassidy R. Sugimoto , Guo Zhang , Blaise Cronin Journal of the American Society for Information Science and Technology. 2012;64(1):2-17. doi: https://doi.org/10.1002/asi.22784 Research on bias in peer review examines scholarly …
Animal to human translation: a systematic scoping review of reported concordance rates
ReferenceCathalijn H. C. Leenaars , Carien Kouwenaar , Frans R. Stafleu , André Bleich , Merel Ritskes-Hoitinga , Rob B. M. De Vries , Franck L. B. Meijboom Journal of Translational Medicine. 2019;17(1):223. doi: 10.1186/s12967-019-1976-2 BACKGROUND: Drug …
Animal testing and its alternatives - the most important omics is economics
ReferenceLucy Meigs , Lena Smirnova , Costanza Rovida , Marcel Leist , Thomas Hartung Alternatives to Animal Experimentation. 2018;35(3):275-305. doi: 10.14573/altex.1807041 For a long time, the discussion about animal testing vs its alternatives centered on …
The impact of conducting preclinical systematic reviews on researchers and their research: A mixed method case study
ReferenceJulia M. L. Menon , Merel Ritskes-Hoitinga , Pandora Pound , Erica van Oort PloS One. 2021;16(12):e0260619. doi: 10.1371/journal.pone.0260619 BACKGROUND: Systematic reviews (SRs) are cornerstones of evidence-based medicine and have contributed …
The Promises of Speeding Up: Changes in Requirements for Animal Studies and Alternatives during COVID-19 Vaccine Approval–A Case Study
ReferenceMerel Ritskes-Hoitinga , Yari Barella , Tineke Kleinhout-Vliek Animals. 2022;12(13):1735. doi: 10.3390/ani12131735 On 21 December 2020, the European Commission granted conditional marketing authorisation for the BNT162b2 COVID-19 vaccine ‘Comirnaty’, …