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Molecular and cellular dynamics of the developing human neocortex
ReferenceLi Wang , Cheng Wang , Juan A. Moriano , Songcang Chen , Guolong Zuo , Arantxa Cebrián-Silla , Shaobo Zhang , Tanzila Mukhtar , Shaohui Wang , Mengyi Song , Lilian Gomes de Oliveira , Qiuli Bi , Jonathan J. Augustin , Xinxin Ge , Mercedes F. Paredes , …
Chromatin accessibility during human first-trimester neurodevelopment
ReferenceCamiel C. A. Mannens , Lijuan Hu , Peter Lönnerberg , Marijn Schipper , Caleb C. Reagor , Xiaofei Li , Xiaoling He , Roger A. Barker , Erik Sundström , Danielle Posthuma , Sten Linnarsson Nature. 2025;647(8088):179-186. doi: 10.1038/s41586-024-07234-1 The …
Injury and therapy in a human spinal cord organoid
ReferenceNozomu Takata , Zhiwei Li , Anna Metlushko , Feng Chen , Nicholas A. Sather , Xinyi Lin , Matthew J. Schipma , Oscar A. Carballo-Molina , Cassandre Jamroz , Madison E. Strong , Cara S. Smith , Yang Yang , Ching M. Wai , Neha Joshi , Jack Kolberg-Edelbrock …
Parkinson's Disease Patient-Specific Striatum Organoids Show Hallmarks of Increased Inflammation
ReferenceKyriaki Barmpa , Claudia Saraiva , Alise Zagare , Mona Tuzza , Joseph Longworth , Elisa Zuccoli , Katrin Hufnagel , Florian Skwirblies , Ronny Schmidt , Dirk Brenner , Christoph Schröder , Jens C. Schwamborn Movement Disorders. ;n/a(n/a). doi: …
Vascular architecture-on-chip: engineering complex blood vessels for reproducing physiological and heterogeneous hemodynamics and endothelial function
ReferenceJennifer D. Lee , Ankit Kumar , Tanmay Mathur , Abhishek Jain Lab on a Chip. 2025;25(11):2620-2631. doi: 10.1039/D4LC00968A Human circulation exhibits significant diversity and heterogeneity of blood vessel shapes. The complex architecture of these …
When peer review drags on: the harm to early career researchers
ReferenceNoemi Felisi , Riccardo Vecchio , Anna Odone Frontiers in Research Metrics and Analytics. 2026;11. doi: 10.3389/frma.2026.1740381 I am an infectious diseases resident and early career researcher (ECR) from Italy interested in global health. In August …
Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow
ReferenceJade Admiraal , Promise O. Emeh , Marleen Bokkers , Sander P. M. de Ruiter , Thomas Olivier , Karla Queiroz , Todd P. Burton , Nienke R. Wevers Fluids and Barriers of the CNS. 2026;23(1):29. doi: 10.1186/s12987-026-00765-x The blood vessels of the central …
Implications of stress for animal welfare and animal-based researchâ€
ReferenceSarah E. Wolfensohn , Vera Baumans , F. Josef van der Staay , Saskia S. Arndt Laboratory Animals. 2025:00236772251396310. doi: 10.1177/00236772251396310 Better animal welfare is essential for better animal-based science. Poor welfare induces stress (and …
Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop
ReferenceTimothy W. Gant , Alistair Boxall , Daniel Burgwinkel , Maryam Zare Jeddi , Ivo Djidrovski , Steffi Friedrichs , Barry Hardy , Thomas Hartung , Daniela Holland , Andreas Karwath , Anne Kienhuis , Nicole Kleinstreuer , Zhoumeng Lin , Emma L. Marczylo , …
The effects of a second pregnancy on women’s brain structure and function
ReferenceM. Straathof , S. Halmans , P. J. W. Pouwels , E. A. Crone , E. Hoekzema Nature Communications. 2026;17(1):1495. doi: 10.1038/s41467-026-69370-8 While we have previously shown that a first pregnancy changes women’s brain structure and resting-state brain …