Search
Regional and institutional trends in assessment for academic promotion
ReferenceB. H. Lim , C. D’Ippoliti , M. Dominik , A. C. Hernández-Mondragón , K. Vermeir , K. K. Chong , H. Hussein , V. S. Morales-Salgado , K. J. Cloete , J. N. Kimengsi , L. Balboa , S. Mondello , T. E. dela Cruz , S. Lopez-Verges , I. Sidi Zakari , A. Simonyan …
Effects of microgravity on human iPSC-derived neural organoids on the International Space Station
ReferenceDavide Marotta , Laraib Ijaz , Lilianne Barbar , Madhura Nijsure , Jason Stein , Nicolette Pirjanian , Ilya Kruglikov , Twyman Clements , Jana Stoudemire , Paula Grisanti , Scott A Noggle , Jeanne F Loring , Valentina Fossati Stem Cells Translational …
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses
ReferenceXin Chen , Mustafa Ghanizada , Vamsee Mallajosyula , Elsa Sola , Robson Capasso , Karan Raj Kathuria , Mark M. Davis Nature Immunology. 2025:1-10. doi: 10.1038/s41590-024-02062-x Here we analyzed the relative contributions of CD4+ regulatory T cells …
Bioelectric stimulation controls tissue shape and size
ReferenceGawoon Shim , Isaac B. Breinyn , Alejandro MartÃnez-Calvo , Sameeksha Rao , Daniel J. Cohen Nature Communications. 2024;15(1):2938. doi: 10.1038/s41467-024-47079-w Epithelial tissues sheath organs and electro-mechanically regulate ion and water transport …
Heart-on-a-chip: a revolutionary organ-on-chip platform for cardiovascular disease modeling
ReferenceBeiqin Liu , Shuyue Wang , Hong Ma , Yulin Deng , Jichen Du , Yimeng Zhao , Yu Chen Journal of Translational Medicine. 2025;23(1):132. doi: 10.1186/s12967-024-05986-y Heart-on-a-chip (HoC) devices have emerged as a powerful tool for studying the human …
Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018
ReferenceOlivier J. Wouters , Martin McKee , Jeroen Luyten JAMA. 2020;323(9):844-853. doi: 10.1001/jama.2020.1166 The mean cost of developing a new drug has been the subject of debate, with recent estimates ranging from $314 million to $2.8 billion.To estimate the …
A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimens
ReferenceGina Bouchard , Weiruo Zhang , Ilayda Ilerten , Irene Li , Asmita Bhattacharya , Yuanyuan Li , Winston Trope , Joseph B. Shrager , Calvin Kuo , Michael G. Ozawa , Amato J. Giaccia , Lu Tian , Sylvia K. Plevritis Nature Communications. 2025;16(1):1392. …
Spatially controlled multicellular differentiation of stem cells using triple factor-releasing metal–organic framework-coated nanoline arrays
ReferenceYeon-Woo Cho , Min-Ji Kang , Joon-Ha Park , Yun-Sik Eom , Tae-Hyung Kim Nature Communications. 2025;16(1):1389. doi: 10.1038/s41467-025-56373-0 Improved in vitro models are needed for regenerative therapy and drug screening. Here, we report on …
Clinical applications of human organoids
ReferenceMonique M. A. Verstegen , Rob P. Coppes , Anne Beghin , Paolo De Coppi , Mattia F. M. Gerli , Nienke de Graeff , Qiuwei Pan , Yoshimasa Saito , Shaojun Shi , Amir A. Zadpoor , Luc J. W. van der Laan Nature Medicine. 2025:1-13. doi: …
Open peer review: promoting transparency in open science
ReferenceDietmar Wolfram , Peiling Wang , Adam Hembree , Hyoungjoo Park Scientometrics. 2020;125(2):1033-1051. doi: 10.1007/s11192-020-03488-4 Open peer review (OPR), where review reports and reviewers’ identities are published alongside the articles, represents …