Placental organoids for drug and biomarker discovery

Nature Reviews Bioengineering. 2026;4(4):288-290. doi: 10.1038/s44222-026-00409-7

Placental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies.

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