00925nas a2200205 4500000000100000000000100001008004100002260001200043653001800055653002300073100002000096700002000116700002000136245005700156856005500213300001200268490000600280520041900286022001400705 2026 d c2026-0410adisease model10aTissue engineering1 aClaire Richards1 aFatemeh Heidari1 aLana McClements00aPlacental organoids for drug and biomarker discovery uhttps://www.nature.com/articles/s44222-026-00409-7 a288-2900 v43 aPlacental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies. a2731-6092