TY - JOUR KW - disease model KW - Tissue engineering AU - Claire Richards AU - Fatemeh Heidari AU - Lana McClements AB - Placental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies. BT - Nature Reviews Bioengineering DA - 2026-04 DO - 10.1038/s44222-026-00409-7 IS - 4 LA - en N2 - Placental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies. PY - 2026 SP - 288 EP - 290 T2 - Nature Reviews Bioengineering TI - Placental organoids for drug and biomarker discovery UR - https://www.nature.com/articles/s44222-026-00409-7 VL - 4 Y2 - 2026-08-12 SN - 2731-6092 ER -