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A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis

Francesca Fagiani, Edoardo Pedrini, Stefano Taverna, Elena Brambilla, Valentina Murtaj, Paola Podini, Francesca Ruffini, Erica Butti, Clarissa Braccia, Annapaola Andolfo, Roberta Magliozzi, Lena Smirnova, Tanja Kuhlmann, Angelo Quattrini, Peter A. Calabresi, Daniel S. Reich, Gianvito Martino, Paola Panina-Bordignon, Martina Absinta
Cell Reports Medicine. 2024:101680. doi: 10.1016/j.xcrm.2024.101680
https://www.cell.com/cell-reports-medicine/abstract/S2666-3791(24)00401-4
Keywords
SOX10
brain organoids
glia-microglia axis
HiPSC
multiple sclerosis
neuroinflammation
oligodendrocytes
single-cell genomics
Library Collection(s)
Nervous system
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The content of this website is adapted from Krebs et al., Author Guide for Addressing Animal Methods Bias in Publishing. Advanced Science. 2023 Aug 30:e2303226. doi: 10.1002/advs.202303226. © 2023 by Krebs et al. is licensed under CC BY 4.0. Advanced Science, published by Wiley-VCH GmbH. Wiley-VCH GmbH does not endorse the COLAAB, nor our use of the content. 

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