Lena Smirnova

Eike Cöllen, Kristina Bartmann, Jonathan Blum, et al. Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2501091

Uwe Marx, Sonja Beken, Zaozao Chen, et al. Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare. ALTEX - Alternatives to animal experimentation. 2025;42(2):204-223. doi:10.14573/altex.2410112

Thomas Hartung, Lena Smirnova. A path forward advancing microphysiological systems. ALTEX - Alternatives to animal experimentation. 2025;42(2):183-203. doi:10.14573/altex.2504091

Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5

Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5

Susan J. Debad, Jason Aungst, Kelly Carstens, et al. State of the science on assessing developmental neurotoxicity using new approach methods. ALTEX - Alternatives to animal experimentation. 2025;42(1):121-144. doi:10.14573/altex.2410231

Alex Rittenhouse, Caroline Krall, Jesse Plotkin, et al. Microglia-containing neural organoids as brain microphysiological systems for long-term culture. Frontiers in Cellular Neuroscience. 2025;19. doi:10.3389/fncel.2025.1616470

Tjitse van der Molen, Alex Spaeth, Mattia Chini, et al. Preconfigured neuronal firing sequences in human brain organoids. Nature Neuroscience. 2025:1-13. doi:10.1038/s41593-025-02111-0

Lena Smirnova, Thomas Hartung. The Promise and Potential of Brain Organoids. Advanced Healthcare Materials. 2024:2302745. doi:10.1002/adhm.202302745

Francesca Fagiani, Edoardo Pedrini, Stefano Taverna, et al. A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis. Cell Reports Medicine. 2024:101680. doi:10.1016/j.xcrm.2024.101680