Humans

Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, et al. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Communications Biology. 2021;4(1):1080. doi:10.1038/s42003-021-02616-x

Hongbing Wang, Paul C. Brown, Edwin C. Y. Chow, et al. 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration. Clinical and Translational Science. 2021;14(5):1659-1680. doi:10.1111/cts.13066

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2

Michael S. Lauer, Jamie Doyle, Joy Wang, Deepshikha Roychowdhury. Associations of topic-specific peer review outcomes and institute and center award rates with funding disparities at the National Institutes of Health. eLife. 2021;10:e67173. doi:10.7554/eLife.67173

Marissa M. Shams-White, Rolando Barajas, Roxanne E. Jensen, et al. Systems epidemiology and cancer: A review of the National Institutes of Health extramural grant portfolio 2013-2018. PloS One. 2021;16(4):e0250061. doi:10.1371/journal.pone.0250061

Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, et al. Cells of the human intestinal tract mapped across space and time. Nature. 2021;597(7875):250-255. doi:10.1038/s41586-021-03852-1

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880

Rachel E. Young, Dan Dongeun Huh. Organ-on-a-chip technology for the study of the female reproductive system. Advanced Drug Delivery Reviews. 2021;173:461-478. doi:10.1016/j.addr.2021.03.010

Hyo-Jin Yoon, Yong Jae Lee, Sewoom Baek, et al. Hormone autocrination by vascularized hydrogel delivery of ovary spheroids to rescue ovarian dysfunctions. Science Advances. 2021;7(18):eabe8873. doi:10.1126/sciadv.abe8873

Amanda M. Clark, Nancy L. Allbritton, Alan Wells. Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology. 2021;71:157-169. doi:10.1016/j.semcancer.2020.06.010