1.
Hongbing Wang, Paul C. Brown, Edwin C. Y. Chow, et al. 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration. Clinical and Translational Science. 2021;14(5):1659-1680. doi:10.1111/cts.13066
Humans
1.
Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2
1.
Jens Puschhof, Cayetano Pleguezuelos-Manzano, Hans Clevers. Organoids and organs-on-chips: Insights into human gut-microbe interactions. Cell Host & Microbe. 2021;29(6):867-878. doi:10.1016/j.chom.2021.04.002
1.
Michael S. Lauer, Jamie Doyle, Joy Wang, Deepshikha Roychowdhury. Associations of topic-specific peer review outcomes and institute and center award rates with funding disparities at the National Institutes of Health. eLife. 2021;10:e67173. doi:10.7554/eLife.67173
1.
Marissa M. Shams-White, Rolando Barajas, Roxanne E. Jensen, et al. Systems epidemiology and cancer: A review of the National Institutes of Health extramural grant portfolio 2013-2018. PloS One. 2021;16(4):e0250061. doi:10.1371/journal.pone.0250061
1.
Amanda M. Clark, Nancy L. Allbritton, Alan Wells. Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology. 2021;71:157-169. doi:10.1016/j.semcancer.2020.06.010
1.
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, et al. Cells of the human intestinal tract mapped across space and time. Nature. 2021;597(7875):250-255. doi:10.1038/s41586-021-03852-1
1.
Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880
1.
Sophie Zaaijer, Amanda Capes-Davis. Ancestry matters: Building inclusivity into preclinical study design. Cell. 2021;184(10):2525-2531. doi:10.1016/j.cell.2021.03.041
1.
Hyo-Jin Yoon, Yong Jae Lee, Sewoom Baek, et al. Hormone autocrination by vascularized hydrogel delivery of ovary spheroids to rescue ovarian dysfunctions. Science Advances. 2021;7(18):eabe8873. doi:10.1126/sciadv.abe8873