Drug Discovery

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Rachel E. Young, Dan Dongeun Huh. Organ-on-a-chip technology for the study of the female reproductive system. Advanced Drug Delivery Reviews. 2021;173:461-478. doi:10.1016/j.addr.2021.03.010
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Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, et al. Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review. Scientific Reports. 2021;11(1):6403. doi:10.1038/s41598-021-85708-2
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Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2
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Alice Maria Giani, Shuibing Chen. Human pluripotent stem cell-based organoids and cell platforms for modelling SARS-CoV-2 infection and drug discovery. Stem Cell Research. 2021;53:102207. doi:10.1016/j.scr.2021.102207
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Smriti Mallapaty. The mini lungs and other organoids helping to beat COVID. Nature. 2021;593(7860):492-494. doi:10.1038/d41586-021-01395-z
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Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088
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Sophie Zaaijer, Amanda Capes-Davis. Ancestry matters: Building inclusivity into preclinical study design. Cell. 2021;184(10):2525-2531. doi:10.1016/j.cell.2021.03.041
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Patrick M. Misun, Burçak Yesildag, Felix Forschler, et al. In Vitro Platform for Studying Human Insulin Release Dynamics of Single Pancreatic Islet Microtissues at High Resolution. Advanced Biosystems. 2020;4(3):e1900291. doi:10.1002/adbi.201900291
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Jun-Hwan Yoo, Mark Donowitz. Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases. World Journal of Gastroenterology. 2019;25(30):4125-4147. doi:10.3748/wjg.v25.i30.4125
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Ben G. Fitzpatrick, Elena Koustova, Yun Wang. Getting personal with the “reproducibility crisis”: interviews in the animal research community. Lab Animal. 2018;47(7):175-177. doi:10.1038/s41684-018-0088-6
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