Drug Discovery

Lorna Ewart, Athanasia Apostolou, Skyler A. Briggs, et al. Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Communications Medicine. 2022;2:154. doi:10.1038/s43856-022-00209-1

Michael Eisenstein. Organoids open fresh paths to biomedical advances. Nature. 2022;612(7940):S34-S35. doi:10.1038/d41586-022-04214-1

Manuela Cassotta, Hugo Geerts, Lise Harbom, et al. The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX. 2022;39(4):694-709. doi:10.14573/altex.2203161

Lucie A. Low, Christine Mummery, Brian R. Berridge, Christopher P. Austin, Danilo A. Tagle. Organs-on-chips: into the next decade. Nature Reviews. Drug Discovery. 2021;20(5):345-361. doi:10.1038/s41573-020-0079-3

Rachel E. Young, Dan Dongeun Huh. Organ-on-a-chip technology for the study of the female reproductive system. Advanced Drug Delivery Reviews. 2021;173:461-478. doi:10.1016/j.addr.2021.03.010

Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, et al. Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review. Scientific Reports. 2021;11(1):6403. doi:10.1038/s41598-021-85708-2

Sophie Zaaijer, Amanda Capes-Davis. Ancestry matters: Building inclusivity into preclinical study design. Cell. 2021;184(10):2525-2531. doi:10.1016/j.cell.2021.03.041

Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088

Smriti Mallapaty. The mini lungs and other organoids helping to beat COVID. Nature. 2021;593(7860):492-494. doi:10.1038/d41586-021-01395-z

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2