Translation and validation

Antje Schmidt-Pogoda, Nadine Bonberg, Mailin Hannah Marie Koecke, et al. Why Most Acute Stroke Studies Are Positive in Animals but Not in Patients: A Systematic Comparison of Preclinical, Early Phase, and Phase 3 Clinical Trials of Neuroprotective Agents. Annals of Neurology. 2020;87(1):40-51. doi:10.1002/ana.25643

Francesca Pistollato, Camilla Bernasconi, Janine McCarthy, et al. Alzheimer’s Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research. Animals (Basel). 2020;10(7):1194. doi:10.3390/ani10071194

Olivier J. Wouters, Martin McKee, Jeroen Luyten. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018. JAMA. 2020;323(9):844-853. doi:10.1001/jama.2020.1166

Rachel L. C. Barrett, Matthew Dawson, Tim B. Dyrby, et al. Differences in Frontal Network Anatomy Across Primate Species. Journal of Neuroscience. 2020;40(10):2094-2107. doi:10.1523/JNEUROSCI.1650-18.2019

John J. Pippin, Sarah E. Cavanaugh, Francesca Pistollato. Animal Research for Alzheimer Disease: Failures of Science and Ethics. In: Kathrin Herrmann, Kimberley Jayne, eds. Animal Experimentation: Working Towards a Paradigm Change. Brill; 2019:480-516. https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.27.

John P. Gluck. Afterword: Evidence over Interests. In: Kathrin Herrmann, Kimberley Jayne, eds. Animal Experimentation. Brill; 2019:689-691. https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.36.

Kathrin Herrmann, Kimberley Jayne, eds. Animal Experimentation: Working Towards a Paradigm Change. Brill; 2019. https://www.jstor.org/stable/10.1163/j.ctvjhzq0f.

Cathalijn H. C. Leenaars, Carien Kouwenaar, Frans R. Stafleu, et al. Animal to human translation: a systematic scoping review of reported concordance rates. Journal of Translational Medicine. 2019;17(1):223. doi:10.1186/s12967-019-1976-2

Chi Heem Wong, Kien Wei Siah, Andrew W Lo. Estimation of clinical trial success rates and related parameters. Biostatistics. 2019;20(2):273-286. doi:10.1093/biostatistics/kxx069

Steffi Bressers, Hester van den Elzen, Cathrin Gräwe, Daphne van den Oetelaar, Pieter H. A. Postma, Sybren K. Schoustra. Policy driven changes in animal research practices: mapping researchers’ attitudes towards animal-free innovations using the Netherlands as an example. Research Integrity and Peer Review. 2019;4:8. doi:10.1186/s41073-019-0067-5