Translation and validation

Désirée H. Veening-Griffioen, Guilherme S. Ferreira, Peter J. K. Van Meer, et al. Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease. European Journal of Pharmacology. 2019;859:172524. doi:10.1016/j.ejphar.2019.172524

Jarrod Bailey, Michael Balls. Recent efforts to elucidate the scientific validity of animal-based drug tests by the pharmaceutical industry, pro-testing lobby groups, and animal welfare organisations. BMC Medical Ethics. 2019;20(1):16. doi:10.1186/s12910-019-0352-3

Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens. Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research. Alternatives to Animal Experimentation. 2019;36(3):343-352. doi:10.14573/altex.1907031

Gail A. Van Norman. Phase II Trials in Drug Development and Adaptive Trial Design. JACC: Basic to Translational Science. 2019;4(3):428-437. doi:10.1016/j.jacbts.2019.02.005

Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041

Pandora Pound, Merel Ritskes-Hoitinga. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. Journal of Translational Medicine. 2018;16(1):304. doi:10.1186/s12967-018-1678-1

Hana Golding, Surender Khurana, Marina Zaitseva. What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? The Importance of Bridging Studies and Species-Independent Correlates of Protection. Cold Spring Harbor Perspectives in Biology. 2018;10(4):a028902. doi:10.1101/cshperspect.a028902

Kathy Archibald, Katya Tsaioun, J. Gerry Kenna, Pandora Pound. Better science for safer medicines: the human imperative. Journal of the Royal Society of Medicine. 2018;111(12):433-438. doi:10.1177/0141076818812783

F. Claire Hankenson, James O. Marx, Christopher J. Gordon, John M. David. Effects of Rodent Thermoregulation on Animal Models in the Research Environment. Comparative Medicine. 2018;68(6):425-438. doi:10.30802/AALAS-CM-18-000049

Ben G. Fitzpatrick, Elena Koustova, Yun Wang. Getting personal with the “reproducibility crisis”: interviews in the animal research community. Lab Animal. 2018;47(7):175-177. doi:10.1038/s41684-018-0088-6