Toxicology

M. Burbank, N. J. Hewitt, F. Gautier, et al. New Approach Methodologies for evaluating Developmental And Reproductive Toxicity potential: review on state of the art, applicability for cosmetic related ingredients and coverage of developmental stages. NAM Journal. 2025:100055. doi:10.1016/j.namjnl.2025.100055

Shu Yang, Kelly E. Carstens, Ibukunoluwa Ipaye, et al. High-throughput cytokine detection platform for evaluation of chemical induced microglial activation. SLAS Technology. 2025;35. doi:10.1016/j.slast.2025.100347

Shivangi Shrimali, Minjun Chen, Dongying Li, Weida Tong. New approach methodologies (NAMs) for drug-induced liver injury (DILI): Where are we now? Drug Discovery Today. 2025;30(9):104452. doi:10.1016/j.drudis.2025.104452

Jacob D. Larson, Sushma Jadalannagari, Jake Chaff, et al. Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip. Scientific Reports. 2025;15(1):28132. doi:10.1038/s41598-025-12846-2

Robert M. Geiger, Shekh M. Rahman, Md Shadiqur Rashid Roni, et al. Assessment of drug permeability using a small airway microphysiological system. Frontiers in Pharmacology. 2025;16. doi:10.3389/fphar.2025.1621775

Argel Islas-Robles, Meera Ramani, Jakeb Phillips, Gertrude-Emilia Costin. New Horizons in Skin Sensitization Assessment of Complex Mixtures: The Use of New Approach Methodologies Beyond Regulatory Approaches. Toxics. 2025;13(8):693. doi:10.3390/toxics13080693

Shivangi Shrimali, Minjun Chen, Dongying Li, Weida Tong. New approach methodologies (NAMs) for drug-induced liver injury (DILI): Where are we now? Drug Discovery Today. 2025:104452. doi:10.1016/j.drudis.2025.104452

Xiaozhong Huang, Yun Ting Soong, Jiahao Wang, et al. HIVIL: A human <i>in vitro</i> inflammatory liver model recapitulates immune-associated drug effects with high predictivity. NAM Journal. 2025;1:100032. doi:10.1016/j.namjnl.2025.100032

Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025. doi:10.1038/d41573-025-00038-6

Katja Graf, José Martin Murrieta-Coxca, Tobias Vogt, et al. Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women. Frontiers in Pharmacology. 2025;16. doi:10.3389/fphar.2025.1528748