Toxicology

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Agnes L. Karmaus, Anna L. Kreutz, Oluwakemi Oyetade, et al. Perspectives on variability of in vivo toxicology studies: considerations for next-generation toxicology. Frontiers in Toxicology. 2026;8. doi:10.3389/ftox.2026.1778353
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Julen Sanz-Serrano, Laura Suter-Dick. Hepatotoxicity: Mechanisms and animal-free prediction models. Toxicology. 2026:154400. doi:10.1016/j.tox.2026.154400
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Andreas Natsch, Peter Griem, Amaia Irizar, et al. Derivation of a Point of Departure using NAMs for application in Quantitative Risk Assessment of fragrance materials. Regulatory Toxicology and Pharmacology. 2026:106052. doi:10.1016/j.yrtph.2026.106052
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Timothy W. Gant, Alistair Boxall, Daniel Burgwinkel, et al. Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop. Archives of Toxicology. 2026. doi:10.1007/s00204-025-04286-8
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Elisabet Berggren, Andrew P. Worth. Managing change while phasing out animal testing in chemical safety assessments – a collection of stakeholder experiences and expectations. NAM Journal. 2026;2:100079. doi:10.1016/j.namjnl.2026.100079
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Xiaozhong Huang, Yun Ting Soong, Jiahao Wang, et al. HIVIL: A human <i>in vitro</i> inflammatory liver model recapitulates immune-associated drug effects with high predictivity. NAM Journal. 2025;1:100032. doi:10.1016/j.namjnl.2025.100032
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Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025. doi:10.1038/d41573-025-00038-6
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Katja Graf, José Martin Murrieta-Coxca, Tobias Vogt, et al. Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women. Frontiers in Pharmacology. 2025;16. doi:10.3389/fphar.2025.1528748
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Monica Piergiovanni, Milena Mennecozzi, Erio Barale-Thomas, et al. Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology. Archives of Toxicology. 2025. doi:10.1007/s00204-024-03922-z
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Eike Cöllen, Kristina Bartmann, Jonathan Blum, et al. Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2501091
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