Toxicology

Jacintha Shenton, Imein Bousnina, Michael Oropallo, et al. Opportunities and insights from pharmaceutical companies on the current use of new approach methodologies in nonclinical safety assessment. Drug Discovery Today. 2025;30(4):104328. doi:10.1016/j.drudis.2025.104328

Maria T. Baltazar, Sophie Cable, Richard Cubberley, et al. Making safety decisions for a sunscreen active ingredient using next-generation risk assessment: Benzophenone-4 case study. ALTEX. 2025;42(3):511-530. doi:10.14573/altex.2501201

Ruxandra Malina Petrescu-Mag, Mathieu Vinken, Dacinia Crina Petrescu. Mapping the ethical and sustainable transition in toxicology: a bibliometric analysis and a review of new approach methodologies. Archives of Toxicology. 2025. doi:10.1007/s00204-025-04209-7

Christopher E. Goldring, Giusy Russomanno, Carmen Pin, et al. Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety. Nature Reviews Drug Discovery. 2025:1-16. doi:10.1038/s41573-025-01308-z

Jia Yao, Jackye Peretz, Ilona Bebenek, et al. FDA/CDER/OND Experience With New Approach Methodologies (NAMs). International Journal of Toxicology. 2025:10915818251384270. doi:10.1177/10915818251384270

Rahul Mittal, Alan Ho, Harini Adivikolanu, et al. Exploring the potential of computer simulation models in drug testing and biomedical research: a systematic review. Frontiers in Pharmacology. 2025;16. doi:10.3389/fphar.2025.1644907

Indra Roux, Anna E. Lindell, Anne Grießhammer, et al. Industrial and agricultural chemicals exhibit antimicrobial activity against human gut bacteria in vitro. Nature Microbiology. 2025;10(12):3107-3121. doi:10.1038/s41564-025-02182-6

Thomas Luechtefeld, Thomas Hartung. Navigating the AI Frontier in Toxicology: Trends, Trust, and Transformation. Current Environmental Health Reports. 2025;12(1):51. doi:10.1007/s40572-025-00514-6

Marie Corradi, Thomas Luechtefeld, Alyanne M. de Haan, et al. The application of natural language processing for the extraction of mechanistic information in toxicology. Frontiers in Toxicology. 2024;6. doi:10.3389/ftox.2024.1393662

Noelia Antón-Bolaños, Irene Faravelli, Tyler Faits, et al. Brain Chimeroids reveal individual susceptibility to neurotoxic triggers. Nature. 2024;631(8019):142-149. doi:10.1038/s41586-024-07578-8