1.
Kai Cheng, Autumn Williams, Anannya Kshirsagar, et al. Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder. APL Bioengineering. 2025;9(3):036118. doi:10.1063/5.0250559
Nervous system
1.
Ruth A. Roberts, Mamta Behl, Helena T. Hogberg, et al. Use of new approach methodologies (NAMs) in epilepsy research and seizure risk assessment. Drug Discovery Today. 2025;31(1):104569. doi:10.1016/j.drudis.2025.104569
1.
Christopher R. Bye, Elizabeth Qian, Katherine Lim, et al. Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy. Nature Neuroscience. 2025:1-13. doi:10.1038/s41593-025-02118-7
1.
Alice E. Stanton, Adele Bubnys, Emre Agbas, et al. Engineered 3D immuno-glial-neurovascular human miBrain model. Proceedings of the National Academy of Sciences. 2025;122(42):e2511596122. doi:10.1073/pnas.2511596122
1.
Simona Lange, Martin Ebeling, Athéna Loye, et al. Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies. Science Translational Medicine. 2025;17(815):eadp7047. doi:10.1126/scitranslmed.adp7047
1.
Tjitse van der Molen, Alex Spaeth, Mattia Chini, et al. Preconfigured neuronal firing sequences in human brain organoids. Nature Neuroscience. 2025:1-13. doi:10.1038/s41593-025-02111-0
1.
Irene Faravelli, Noelia Antón-Bolaños, Juliana R. Brown, Paola Arlotta. Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain. Annual Review of Genomics and Human Genetics. 2025;26(Volume 26, 2025):299-320. doi:10.1146/annurev-genom-111522-014009
1.
Alice E. Stanton, Adele Bubnys, Emre Agbas, et al. Engineered 3D immuno-glial-neurovascular human miBrain model. Proceedings of the National Academy of Sciences. 2025;122(42):e2511596122. doi:10.1073/pnas.2511596122
1.
Hyehyun Kim, Gregory Girardi, Allison Pickle, Testaverde S. Kim, Erkin Seker. Microfluidic tools to model, monitor, and modulate the gut–brain axis. Biomicrofluidics. 2025;19(2):021301. doi:10.1063/5.0253041
1.
Laura Castro-Aldrete, Melanie Einsiedler, Carla CunÃ-López, et al. Modelling sex differences of neurological disorders in vitro. Nature Reviews Bioengineering. 2025:1-22. doi:10.1038/s44222-025-00355-w