Nervous system

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Alice E. Stanton, Adele Bubnys, Emre Agbas, et al. Engineered 3D immuno-glial-neurovascular human miBrain model. Proceedings of the National Academy of Sciences. 2025;122(42):e2511596122. doi:10.1073/pnas.2511596122
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Alexander G. Bury, Alicja Olejnik, Chiara Tocco, et al. Investigating the ageing-Parkinson’s disease nexus: standardisation of in vitro models and techniques by the PD-AGE network. npj Parkinson’s Disease. 2025;11(1):289. doi:10.1038/s41531-025-01137-2
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Kaveena Autar, Xiufang Guo, Haley Powell, et al. Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics. Biomedicine & Pharmacotherapy. 2025;192:118556. doi:10.1016/j.biopha.2025.118556
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Catarina M. Gomes, Daniel Simão, Carolina Cardoso Gonçalves, et al. Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids. iScience. 2025;28(9). doi:10.1016/j.isci.2025.113246
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Kai Cheng, Autumn Williams, Anannya Kshirsagar, et al. Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder. APL Bioengineering. 2025;9(3):036118. doi:10.1063/5.0250559
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Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5
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Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5
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Xianwei Chen, Guoqiang Sun, Lizhao Feng, E. Tian, Yanhong Shi. Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids. Communications Biology. 2025;8(1):1-11. doi:10.1038/s42003-024-07401-0
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Anna Pagliaro, Francesco Andreatta, Roxy Finger, Benedetta Artegiani, Delilah Hendriks. Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling. Nature Protocols. 2025:1-38. doi:10.1038/s41596-024-01107-7
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