1.
Chi Heem Wong, Kien Wei Siah, Andrew W Lo. Estimation of clinical trial success rates and related parameters. Biostatistics. 2019;20(2):273-286. doi:10.1093/biostatistics/kxx069
Translation and validation
1.
Steffi Bressers, Hester van den Elzen, Cathrin Gräwe, Daphne van den Oetelaar, Pieter H. A. Postma, Sybren K. Schoustra. Policy driven changes in animal research practices: mapping researchers’ attitudes towards animal-free innovations using the Netherlands as an example. Research Integrity and Peer Review. 2019;4:8. doi:10.1186/s41073-019-0067-5
1.
Nora Franzen, Wim H. van Harten, Valesca P. Retèl, Peter Loskill, Janny van den Eijnden-van Raaij, Maarten IJzerman. Impact of organ-on-a-chip technology on pharmaceutical R&D costs. Drug Discovery Today. 2019;24(9):1720-1724. doi:10.1016/j.drudis.2019.06.003
1.
Gail A. Van Norman. Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach? JACC. Basic to translational science. 2019;4(7):845-854. doi:10.1016/j.jacbts.2019.10.008
1.
Désirée H. Veening-Griffioen, Guilherme S. Ferreira, Peter J. K. Van Meer, et al. Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease. European Journal of Pharmacology. 2019;859:172524. doi:10.1016/j.ejphar.2019.172524
1.
Jarrod Bailey, Michael Balls. Recent efforts to elucidate the scientific validity of animal-based drug tests by the pharmaceutical industry, pro-testing lobby groups, and animal welfare organisations. BMC Medical Ethics. 2019;20(1):16. doi:10.1186/s12910-019-0352-3
1.
Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens. Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research. Alternatives to Animal Experimentation. 2019;36(3):343-352. doi:10.14573/altex.1907031
1.
Gail A. Van Norman. Phase II Trials in Drug Development and Adaptive Trial Design. JACC: Basic to Translational Science. 2019;4(3):428-437. doi:10.1016/j.jacbts.2019.02.005
1.
Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041
1.
Pandora Pound, Merel Ritskes-Hoitinga. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. Journal of Translational Medicine. 2018;16(1):304. doi:10.1186/s12967-018-1678-1