Ethics, policy, and legislation

Ruxandra Malina Petrescu-Mag, Mathieu Vinken, Dacinia Crina Petrescu. Mapping the ethical and sustainable transition in toxicology: a bibliometric analysis and a review of new approach methodologies. Archives of Toxicology. 2025. doi:10.1007/s00204-025-04209-7

Tessel B. Wijne, Wouter P. C. Boon, Anne S. Kienhuis, Ellen H. M. Moors, Jarno Hoekman. Pursuing societal impact in research projects on NAM development: An analysis of routes to impact. NAM Journal. 2025;1:100050. doi:10.1016/j.namjnl.2025.100050

Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025;24(6):401-402. doi:10.1038/d41573-025-00038-6

Sarah A Carratt, Christina L Zuch de Zafra, Elias Oziolor, et al. An industry perspective on the FDA Modernization Act 2.0/3.0: potential next steps for sponsors to reduce animal use in drug development. Toxicological Sciences. 2025;203(1):28-34. doi:10.1093/toxsci/kfae122

John J. Pippin, Jarrod Bailey, Mark Kennedy, et al. Institutional animal care and use committees and the challenges of evaluating animal research proposals. Research Integrity and Peer Review. 2025;10(1):11. doi:10.1186/s41073-025-00169-9

Lauren Hope, Jarrod Bailey. Breaking down the barriers to animal-free research. Alternatives to Laboratory Animals. 2025;53(4):215-231. doi:10.1177/02611929251349465

Surat Parvatam. India races to raise animal-free drug testing standards. Nature India. 2025. doi:10.1038/d44151-025-00151-w

Fred Schwaller. A mental-health crisis plagues PhDs — these evidence-led initiatives offer help. Nature. 2025. doi:10.1038/d41586-025-01083-2

U.S. National Institutes of Health. NIH to prioritize human-based research technologies. https://www.nih.gov/news-events/news-releases/nih-prioritize-human-based-research-technologies. Published 2025.

Thomas Hartung. The turning point: April 2025 marks historic shift in US animal testing policy. ALTEX - Alternatives to animal experimentation. 2025. doi:10.14573/altex.2504301