Search
Microphysiological systems for human aging research
ReferenceSeungman Park , Thomas C. Laskow , Jingchun Chen , Prasun Guha , Buddhadeb Dawn , Deok-Ho Kim Aging Cell. 2024;23(3):e14070. doi: 10.1111/acel.14070 Recent advances in microphysiological systems (MPS), also known as organs-on-a-chip (OoC), enable the …
Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications
ReferenceSurjendu Maity , Tamanna Bhuyan , Christopher Jewell , Satoru Kawakita , Saurabh Sharma , Huu Tuan Nguyen , Alireza Hassani Najafabadi , Menekse Ermis , Natashya Falcone , Junjie Chen , Kalpana Mandal , Danial Khorsandi , Can Yilgor , Auveen Choroomi , …
Human immune organoids to decode B cell response in healthy donors and patients with lymphoma
ReferenceZhe Zhong , Manuel Quiñones-Pérez , Zhonghao Dai , Valeria M. Juarez , Eshant Bhatia , Christopher R. Carlson , Shivem B. Shah , Anjali Patel , Zhou Fang , Thomas Hu , Mayar Allam , Sakeenah L. Hicks , Mansi Gupta , Sneh Lata Gupta , Ethan Weeks , …
Generation and long-term culture of human cerebellar organoids from pluripotent stem cells
ReferenceAlexander Atamian , Marcella Birtele , Negar Hosseini , Giorgia Quadrato Nature Protocols. 2024:1-32. doi: 10.1038/s41596-024-01093-w The advancement of research on human cerebellar development and diseases has been hindered by the lack of a cell-based …
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
ReferenceAmanda Andersson-Rolf , Kelvin Groot , Jeroen Korving , Harry Begthel , Maaike A. J. Hanegraaf , Michael VanInsberghe , Fredrik Salmén , Stieneke van den Brink , Carmen Lopez-Iglesias , Peter J. Peters , Daniel Krueger , Joep Beumer , Maarten H. Geurts , …
Development of a novel gut microphysiological system that facilitates assessment of drug absorption kinetics in gut
ReferenceTomoki Imaoka , Reiko Onuki-Nagasaki , Hiroshi Kimura , Kempei Tai , Mitsuharu Ishii , Ayaka Nozue , Ikuko Kaisaki , Misa Hoshi , Kengo Watanabe , Kazuya Maeda , Takashi Kamizono , Takahiro Yoshioka , Takashi Fujimoto , Taku Satoh , Hiroko Nakamura , …
Generating human neural diversity with a multiplexed morphogen screen in organoids
ReferenceNeal D. Amin , Kevin W. Kelley , Konstantin Kaganovsky , Massimo Onesto , Jin Hao , Yuki Miura , James P. McQueen , Noah Reis , Genta Narazaki , Tommy Li , Shravanti Kulkarni , Sergey Pavlov , Sergiu P. Pașca Cell Stem Cell. 2024;31(12):1831-1846.e9. doi: …
Patterned gastrointestinal monolayers with bilateral access as observable models of parasite gut infection
ReferenceMoritz Hofer , Maria A. Duque-Correa , Matthias P. Lutolf Nature Biomedical Engineering. 2024:1-11. doi: 10.1038/s41551-024-01313-4 Organoids for modelling the physiology and pathology of gastrointestinal tissues are constrained by a poorly accessible …
Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
ReferenceDorit Trudler , Swagata Ghatak , Michael Bula , James Parker , Maria Talantova , Melissa Luevanos , Sergio Labra , Titas Grabauskas , Sarah Moore Noveral , Mayu Teranaka , Emily Schahrer , Nima Dolatabadi , Clare Bakker , Kevin Lopez , Abdullah Sultan , …
The Promise and Potential of Brain Organoids
ReferenceLena Smirnova , Thomas Hartung Advanced Healthcare Materials. 2024;13(21):2302745. doi: 10.1002/adhm.202302745 Brain organoids are 3D in vitro culture systems derived from human pluripotent stem cells that self-organize to model features of the …