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Test No. 442E: In Vitro Skin Sensitisation: In Vitro Skin Sensitisation assays addressing the Key Event on activation of dendritic cells on the Adverse Outcome Pathway for Skin Sensitisation
ReferenceOrganisation for Economic Co-operation and Development OECD Guidelines for the Testing of Chemicals, Section 4. Paris: Organisation for Economic Co-operation and Development; 2024. The present Key Event based Test Guideline (TG) addresses the human health …
Critical Toponymies: The Contested Politics of Place Naming
ReferenceLawrence D. Berg , Jani Vuolteenaho Re-materialising Cultural Geography. London: Routledge; 2009:306. While place names have long been studied by a few devoted specialists, approaches to them have been traditionally empiricist and uncritical in character. …
Test No. 442E: In Vitro Skin Sensitisation: In Vitro Skin Sensitisation assays addressing the Key Event on activation of dendritic cells on the Adverse Outcome Pathway for Skin Sensitisation
ReferenceOrganisation for Economic Co-operation and Development OECD Guidelines for the Testing of Chemicals, Section 4. Paris: Organisation for Economic Co-operation and Development; 2024. The present Key Event based Test Guideline (TG) addresses the human health …
Manuscript Preparation
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Manuscript Preparation Because animal methods bias can result in publication delays or even manuscript rejection, authors who use nonanimal modeling systems should take preventive steps to avoid these negative outcomes. The first step to counter animal …
Webinar Recordings
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Webinar Recordings Animal-Free Workshop Series for Early-Career Researchers: Workshop No. 5, Addressing the Preference for Animal-Based Research Methods How to Advocate for Fair Funding and Overcome Animal Methods Bias To accompany this webinar, please …
REACH out-numbered! The future of REACH and animal numbers
ReferenceCostanza Rovida , Francois Busquet , Marcel Leist , Thomas Hartung ALTEX - Alternatives to Animal Experimentation. 2023;40(3):367-388. doi: 10.14573/altex.2307121 The EU’s REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) …
Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)
ReferenceSzczepan W. Baran , Paul C. Brown , Andreas R. Baudy , Suzanne C. Fitzpatrick , Christopher Frantz , Aaron Fullerton , Jinping Gan , Rhiannon N. Hardwick , Kathleen M. Hillgren , Anna K. Kopec , Jennifer L. Liras , Donna L. Mendrick , Ryan Nagao , William …
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis
ReferenceBrian W. Kunkle , Michael Schmidt , Hans-Ulrich Klein , Adam C. Naj , Kara L. Hamilton-Nelson , Eric B. Larson , Denis A. Evans , Phil L. De Jager , Paul K. Crane , Joe D. Buxbaum , Nilufer Ertekin-Taner , Lisa L. Barnes , M. Daniele Fallin , Jennifer J. …
Microfluidic organs-on-chips
ReferenceSangeeta N. Bhatia , Donald E. Ingber Nature Biotechnology. 2014;32(8):760-772. doi: 10.1038/nbt.2989 Organ-level physiology is recapitulated in vitro by culturing cells in perfused, microfluidic devices. https://www.nature.com/articles/nbt.2989 Keywords …
Organs-on-chips at the frontiers of drug discovery
ReferenceEric W. Esch , Anthony Bahinski , Dongeun Huh Nature Reviews Drug Discovery. 2015;14(4):248-260. doi: 10.1038/nrd4539 Microengineered cell culture systems are becoming sufficiently sophisticated that they can recapitulate many of the phenomena observed in …