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BimmoH: Biomedical models Hub
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BimmoH: Biomedical models Hub A human biology based curated database designed to structure and consolidate information about models to support biomedical research. https://bimmoh.eu/ Resource type Database Access requirements …
The impact of conducting preclinical systematic reviews on researchers and their research: A mixed method case study
ReferenceJulia M. L. Menon , Merel Ritskes-Hoitinga , Pandora Pound , Erica van Oort PloS One. 2021;16(12):e0260619. doi: 10.1371/journal.pone.0260619 BACKGROUND: Systematic reviews (SRs) are cornerstones of evidence-based medicine and have contributed …
GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancer
ReferenceCarly Strelez , Francesca Battaglin , Rachel Perez , Yan Yang , Christopher Cherry , Joshua Millstein , Ah Young Yoon , John S. Chlystek , Ethan Canfield , Bethany Haliday , Curran Shah , Kimya Ghaffarian , Shivani Soni , Hannah Jiang , Roy Lau , Aaron …
Status of animal experimentation in nutrition and dietetic research: Policies of 100 leading journals and new approach methodologies
ReferenceMaximilian Andreas Storz , Elizabeth Dean Accountability in Research. :1-19. doi: 10.1080/08989621.2024.2398104 Given animal research is challenged with inadequacies, e.g., animal-to-human knowledge translation, ethical considerations, and cost:benefit, …
Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder
ReferenceKai Cheng , Autumn Williams , Anannya Kshirsagar , Sai Kulkarni , Rakesh Karmacharya , Deok-Ho Kim , Sridevi V. Sarma , Annie Kathuria APL Bioengineering. 2025;9(3):036118. doi: 10.1063/5.0250559 Neuropsychiatric disorders such as schizophrenia (SCZ) and …
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression
ReferenceRina Hashimoto , Junya Takahashi , Keisuke Shirakura , Risa Funatsu , Kaori Kosugi , Sayaka Deguchi , Masaki Yamamoto , Yugo Tsunoda , Maaya Morita , Kosuke Muraoka , Masato Tanaka , Tomoaki Kanbara , Shota Tanaka , Shigeyuki Tamiya , Nagisa Tokunoh , …
Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip
ReferenceLonglong Si , Haiqing Bai , Crystal Yuri Oh , Lei Jin , Rachelle Prantil-Baun , Donald E. Ingber , Heba H. Mostafa Microbiology Spectrum. 2021;9(2):e00257-21. doi: 10.1128/Spectrum.00257-21 Human-to-human transmission of viruses, such as influenza viruses …
Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology
ReferenceAlexandra Sontheimer-Phelps , David B. Chou , Alessio Tovaglieri , Thomas C. Ferrante , Taylor Duckworth , Cicely Fadel , Viktoras Frismantas , Arlene D. Sutherland , Sasan Jalili-Firoozinezhad , Magdalena Kasendra , Eric Stas , James C. Weaver , Camilla …
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro
ReferenceBryan A. Hassell , Girija Goyal , Esak Lee , Alexandra Sontheimer-Phelps , Oren Levy , Christopher S. Chen , Donald E. Ingber Cell Reports. 10;21(2):508-516. doi: 10.1016/j.celrep.2017.09.043 Here, we show that microfluidic organ-on-a-chip (organ chip) …
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
ReferenceAnna Herland , Ben M. Maoz , Debarun Das , Mahadevabharath R. Somayaji , Rachelle Prantil-Baun , Richard Novak , Michael Cronce , Tessa Huffstater , Sauveur S. F. Jeanty , Miles Ingram , Angeliki Chalkiadaki , David Benson Chou , Susan Marquez , Aaron …