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Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy

Tianping Peng, Xiujian Ma, Wei Hua, Changwen Wang, Youjun Chu, Meng Sun, Valentina Fermi, Stefan Hamelmann, Katharina Lindner, Chunxuan Shao, Julia Zaman, Weili Tian, Yue Zhuo, Yassin Harim, Nadja Stöffler, Linda Hammann, Qungen Xiao, Xiaoliang Jin, Rolf Warta, Catharina Lotsch, Xuran Zhuang, Yuan Feng, Minjie Fu, Xin Zhang, Jinsen Zhang, Hao Xu, Fufang Qiu, Liqian Xie, Yi Zhang, Wei Zhu, Zunguo Du, Lorena Salgueiro, Mark Schneider, Florian Eichhorn, Arthur Lefevre, Stefan Pusch, Valery Grinevich, Miriam Ratliff, Sonja Loges, Lukas Bunse, Felix Sahm, Yangfei Xiang, Andreas Unterberg, Andreas von Deimling, Michael Platten, Christel Herold-Mende, Yonghe Wu, Hai-Kun Liu, Ying Mao
Cell Stem Cell. 2025. doi: 10.1016/j.stem.2025.01.002
https://www.cell.com/cell-stem-cell/abstract/S1934-5909(25)00002-5
Keywords
brain metastasis
glioblastoma
patient tumor organoid
predictive patient model
temozolomide
tumor heterogeneity
Library Collection(s)
Cancer
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The content of this website is adapted from Krebs et al., Author Guide for Addressing Animal Methods Bias in Publishing. Advanced Science. 2023 Aug 30:e2303226. doi: 10.1002/advs.202303226. © 2023 by Krebs et al. is licensed under CC BY 4.0. Advanced Science, published by Wiley-VCH GmbH. Wiley-VCH GmbH does not endorse the COLAAB, nor our use of the content. 

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