Functional siRNA Delivery via Jet Nebulization: Proof-of-Concept IL-1ß Silencing in Macrophage-like THP-1 Cells

Duy Bao Tran Nguyen, Ahmed S. M. Ali, Dongwei Wu, Johanna Berg, Daniel C. Lauster, Jens Kurreck, Beatrice Tolksdorf
International Journal of Molecular Sciences. 2026;27(6). doi: 10.3390/ijms27062915

The efficient delivery of small interfering RNAs (siRNAs) to immune and respiratory cells represents a key methodological challenge in developing inha...

https://www.mdpi.com/1422-0067/27/6/2915
Keywords
IL-1β knockdown
aerosolized delivery
inhaled RNAi
jet nebulizer
nebulization
siRNA
Library Collection(s)
Bioengineering and model development
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