Cell villages and Dirichlet modeling map human cell fitness genetics

Chloe Hanson, Timothy Derebenskiy, Ana Rodriguez Vega, Yashika S. Kamte, Rachel G. Fox, Laila Sathe, Hannah Lambing, Tyler E. Dietterich, Derek Hawes, Ralda Nehme, Olli Pietiläinen, Aarno Palotie, Patrick Allard, Harold Pimentel, Michael F. Wells

The American Journal of Human Genetics. 2026. doi: 10.1016/j.ajhg.2026.07.005

https://www.cell.com/ajhg/abstract/S0002-9297(26)00271-5

Keywords

16p11.2 deletion

Dirichlet model

Gene-Environment Interaction

neural progenitor cells

Library Collection(s)

Population and variability