Population and variability

Jesse Weidema, Hanna Lammertse, Martine de Vries, Christine Mummery, Megan Munsie, Nienke de Graeff. Diversity-in-a-dish: A practical framework for hiPSC model development. Stem Cell Reports. 2026. doi:10.1016/j.stemcr.2026.102858

Felicity T. Enders, Philip M. Alberti, Elizabeth H. Golembiewski, et al. Measure Racism, Not Just Race: Recommendations for Scientific Practice. American Journal of Public Health. 2026;116(3):300-303. doi:10.2105/AJPH.2025.308393

Melpomeni Platani, Hao Jiang, Lindsay Davidson, et al. Screening for variable drug responses using human iPSC cohorts. PloS One. 2025;20(5):e0323953. doi:10.1371/journal.pone.0323953

Kian Hong Kock, Le Min Tan, Kyung Yeon Han, et al. Asian diversity in human immune cells. Cell. 2025;188(8):2288-2306.e24. doi:10.1016/j.cell.2025.02.017

Noelia Antón-Bolaños, Irene Faravelli, Tyler Faits, et al. Brain Chimeroids reveal individual susceptibility to neurotoxic triggers. Nature. 2024;631(8019):142-149. doi:10.1038/s41586-024-07578-8

Suel-Kee Kim, Seungmae Seo, Genevieve Stein-O’Brien, et al. Individual variation in the emergence of anterior-to-posterior neural fates from human pluripotent stem cells. Stem Cell Reports. 2024;19(9):1336-1350. doi:10.1016/j.stemcr.2024.07.004

Li Pang, Chengzhong Cai, Praful Aggarwal, et al. Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs-a proof-of-concept study with doxorubicin. Toxicological Sciences: An Official Journal of the Society of Toxicology. 2024;200(1):79-94. doi:10.1093/toxsci/kfae041

Alexandra R. Harris, Gatikrushna Panigrahi, Huaitian Liu, et al. Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry. Cancer Research Communications. 2023;3(10):2014-2029. doi:10.1158/2767-9764.CRC-23-0236

Julia Y. Co, Jessica A. Klein, Serah Kang, Kimberly A. Homan. Toward Inclusivity in Preclinical Drug Development: A Proposition to Start with Intestinal Organoids. Advanced Biology. 2023;7(12):2200333. doi:10.1002/adbi.202200333

Helena Niobe Renate Gutleb, Arno Christian Gutleb. A Short History of the Consideration of Sex Differences in Biomedical Research — Lessons for the In Vitro Community from Animal Models and Human Clinical Trials. Alternatives to Laboratory Animals. 2023;51(2):144-150. doi:10.1177/02611929231156720