Humans

Laura Pellegrini, Anna Albecka, Donna L. Mallery, et al. SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids. Cell Stem Cell. 2020;27(6):951-961.e5. doi:10.1016/j.stem.2020.10.001

Mart M. Lamers, Joep Beumer, Jelte van der Vaart, et al. SARS-CoV-2 productively infects human gut enterocytes. Science (New York, N.Y.). 2020;369(6499):50-54. doi:10.1126/science.abc1669

Jie Zhou, Cun Li, Xiaojuan Liu, et al. Infection of bat and human intestinal organoids by SARS-CoV-2. Nature Medicine. 2020;26(7):1077-1083. doi:10.1038/s41591-020-0912-6

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182(6):1623-1640.e34. doi:10.1016/j.cell.2020.08.013

Uwe Marx, Takafumi Akabane, Tommy B. Andersson, et al. Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development. ALTEX. 2020;37(3):365-394. doi:10.14573/altex.2001241

S. Vincent Rajkumar. The high cost of prescription drugs: causes and solutions. Blood Cancer Journal. 2020;10(6):71. doi:10.1038/s41408-020-0338-x

Patrick M. Misun, Burçak Yesildag, Felix Forschler, et al. In Vitro Platform for Studying Human Insulin Release Dynamics of Single Pancreatic Islet Microtissues at High Resolution. Advanced Biosystems. 2020;4(3):e1900291. doi:10.1002/adbi.201900291

Eric Vallabh Minikel, Konrad J. Karczewski, Hilary C. Martin, et al. Evaluating drug targets through human loss-of-function genetic variation. Nature. 2020;581(7809):459-464. doi:10.1038/s41586-020-2267-z

Junyue Cao, Diana R. O’Day, Hannah A. Pliner, et al. A human cell atlas of fetal gene expression. Science (New York, N.Y.). 2020;370(6518):eaba7721. doi:10.1126/science.aba7721

Cathalijn H. C. Leenaars, Carien Kouwenaar, Frans R. Stafleu, et al. Animal to human translation: a systematic scoping review of reported concordance rates. Journal of Translational Medicine. 2019;17(1):223. doi:10.1186/s12967-019-1976-2