Disease Models, Animal

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Min Liu, Jonathan G. Faris, Amanda R. Panfil, Cody J. Warren. How new approach methods are reshaping virology research. Journal of Virology. 2026;100(4):e0132625. doi:10.1128/jvi.01326-25
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Inês Falcão-Pires. Alternatives to animal experimentation in cardiovascular research: human models of disease and biobanking. European Heart Journal. 2024;45(5):324-327. doi:10.1093/eurheartj/ehad709
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Sonya Kouthouridis, Eleanor Robson, Alicia Hartung, Sandeep Raha, Boyang Zhang. Se(XY) matters: the importance of incorporating sex in microphysiological models. Trends in Biotechnology. 2022;40(11):1284-1298. doi:10.1016/j.tibtech.2022.04.005
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Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, et al. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Communications Biology. 2021;4(1):1080. doi:10.1038/s42003-021-02616-x
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Sabrina Ehnert, Helen Rinderknecht, Romina H. Aspera-Werz, Victor Häussling, Andreas K. Nussler. Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models. Archives of Toxicology. 2020;94(12):3937-3958. doi:10.1007/s00204-020-02906-z
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Norman Sachs, Angelos Papaspyropoulos, Domenique D. Zomer-van Ommen, et al. Long-term expanding human airway organoids for disease modeling. The EMBO journal. 2019;38(4):e100300. doi:10.15252/embj.2018100300
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Pandora Pound, Merel Ritskes-Hoitinga. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. Journal of Translational Medicine. 2018;16(1):304. doi:10.1186/s12967-018-1678-1
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Susan Bridgwood Green. Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Medical Ethics. 2015;16:53. doi:10.1186/s12910-015-0043-7
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Jarrod Bailey. Monkey-based research on human disease: the implications of genetic differences. Alternatives to Laboratory Animals. 2014;42(5):287-317. doi:10.1177/026119291404200504
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Robert A. J. Matthews. Medical progress depends on animal models - doesn’t it? Journal of the Royal Society of Medicine. 2008;101(2):95-98. doi:10.1258/jrsm.2007.070164
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