brain organoids

Ronit Mohapatra, Dowlette-Mary Alam El Din, Hanyu Zhao, Thomas Hartung, Lena Smirnova. Towards learning and memory risk assessment with human brain organoids: barriers and opportunities. Frontiers in Toxicology. 2026;8. doi:10.3389/ftox.2026.1783893

Cristina Dolciotti, Marco Righi, Eleonora Grecu, et al. The translational power of Alzheimer's-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history. Frontiers in Cellular Neuroscience. 2025;19. doi:10.3389/fncel.2025.1553642

Gulimiheranmu Maisumu, Stephanie Willerth, Michael Nestor, et al. Brain organoids: building higher-order complexity and neural circuitry models. Trends in Biotechnology. 2025. doi:10.1016/j.tibtech.2025.02.009

Wei Wu, Faiza Anas, Baran Koc, et al. Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs. Biomedicine & Pharmacotherapy. 2025;186:118021. doi:10.1016/j.biopha.2025.118021

Eyal Bar-Kochba, Catherine M. Carneal, Vanessa D. Alphonse, et al. Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures. Frontiers in Bioengineering and Biotechnology. 2025;13. doi:10.3389/fbioe.2025.1553609

Pamela E. Capendale, Anoop T. Ambikan, Inés García-Rodríguez, et al. Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids. Cellular and Molecular Life Sciences. 2025;82(1):382. doi:10.1007/s00018-025-05926-z

Francesca Fagiani, Edoardo Pedrini, Stefano Taverna, et al. A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis. Cell Reports Medicine. 2024:101680. doi:10.1016/j.xcrm.2024.101680

Itzy E. Morales Pantoja, Lixuan Ding, Paulo E. C. Leite, et al. A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems. Advanced Biology. 2024;8(8):2300198. doi:10.1002/adbi.202300198

Jonas Cerneckis, Guojun Bu, Yanhong Shi. Pushing the boundaries of brain organoids to study Alzheimer’s disease. Trends in Molecular Medicine. 2023;29(8):659-672. doi:10.1016/j.molmed.2023.05.007

Sara Guerreiro, Patrícia Maciel. Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and Challenges. Cells. 2023;12(4):538. doi:10.3390/cells12040538