amyotrophic lateral sclerosis

Deepti Lall, Michael J. Workman, Samuel Sances, et al. An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier. Cell Stem Cell. 2025;32(7):1139-1153.e7. doi:10.1016/j.stem.2025.05.015

Jakub Scaber, Iona Thomas-Wright, Alex J. Clark, et al. Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons. Stem Cell Reports. 2024;19(7):957-972. doi:10.1016/j.stemcr.2024.05.008

Louise Miny, Benoît G. C. Maisonneuve, Isabelle Quadrio, Thibault Honegger. Modeling Neurodegenerative Diseases Using In Vitro Compartmentalized Microfluidic Devices. Frontiers in Bioengineering and Biotechnology. 2022;10:919646. doi:10.3389/fbioe.2022.919646

Terry C. Burns, Matthew D. Li, Swapnil Mehta, Ahmed J. Awad, Alexander A. Morgan. Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: A systematic bioinformatics-based critique of preclinical models. European Journal of Pharmacology. 2015;759:101-117. doi:10.1016/j.ejphar.2015.03.021