Humans

Janet Piñero, Laura I. Furlong, Ferran Sanz. In silico models in drug development: where we are. Current Opinion in Pharmacology. 2018;42:111-121. doi:10.1016/j.coph.2018.08.007

Sang Hun Lee, SoonGweon Hong, Jihwan Song, et al. Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids. Advanced Healthcare Materials. 2018;7(2). doi:10.1002/adhm.201701111

Dorothée Diogo, Chao Tian, Christopher S. Franklin, et al. Phenome-wide association studies across large population cohorts support drug target validation. Nature Communications. 2018;9(1):4285. doi:10.1038/s41467-018-06540-3

Catherine C. Bell, Anita C. A. Dankers, Volker M. Lauschke, et al. Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study. Toxicological Sciences: An Official Journal of the Society of Toxicology. 2018;162(2):655-666. doi:10.1093/toxsci/kfx289

Anke Guhr, Sabine Kobold, Stefanie Seltmann, Andrea E. M. Seiler Wulczyn, Andreas Kurtz, Peter Löser. Recent Trends in Research with Human Pluripotent Stem Cells: Impact of Research and Use of Cell Lines in Experimental Research and Clinical Trials. Stem Cell Reports. 2018;11(2):485-496. doi:10.1016/j.stemcr.2018.06.012

A. S. Khazali, A. M. Clark, A. Wells. A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. Stem Cell Reviews and Reports. 2017;13(3):364-380. doi:10.1007/s12015-017-9735-3

Eduard Batlle, Hans Clevers. Cancer stem cells revisited. Nature Medicine. 2017;23(10):1124-1134. doi:10.1038/nm.4409

William G. Kaelin. Common pitfalls in preclinical cancer target validation. Nature Reviews. Cancer. 2017;17(7):425-440. doi:10.1038/nrc.2017.32

Shuo Xiao, Jonathan R. Coppeta, Hunter B. Rogers, et al. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nature Communications. 2017;8:14584. doi:10.1038/ncomms14584

Helena Kilpinen, Angela Goncalves, Andreas Leha, et al. Common genetic variation drives molecular heterogeneity in human iPSCs. Nature. 2017;546(7658):370-375. doi:10.1038/nature22403