Humans

Aroon D. Hingorani, Valerie Kuan, Chris Finan, et al. Improving the odds of drug development success through human genomics: modelling study. Scientific Reports. 2019;9(1):18911. doi:10.1038/s41598-019-54849-w

Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041

A. Jain, R. Barrile, A. D. van der Meer, et al. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical Pharmacology and Therapeutics. 2018;103(2):332-340. doi:10.1002/cpt.742

Shurong Hou, Hervé Tiriac, Banu Priya Sridharan, et al. Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. SLAS discovery: advancing life sciences R & D. 2018;23(6):574-584. doi:10.1177/2472555218766842

Kathy Archibald, Katya Tsaioun, J. Gerry Kenna, Pandora Pound. Better science for safer medicines: the human imperative. Journal of the Royal Society of Medicine. 2018;111(12):433-438. doi:10.1177/0141076818812783

Jarno Drost, Hans Clevers. Organoids in cancer research. Nature Reviews. Cancer. 2018;18(7):407-418. doi:10.1038/s41568-018-0007-6

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010

James T. Neal, Xingnan Li, Junjie Zhu, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175(7):1972-1988.e16. doi:10.1016/j.cell.2018.11.021

Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Cell Stem Cell. 2018;22(3):310-324. doi:10.1016/j.stem.2018.02.011

Jarrod Bailey, Shiranee Pereira. Advances in neuroscience imply that harmful experiments in dogs are unethical. Journal of Medical Ethics. 2018;44(1):47-52. doi:10.1136/medethics-2016-103630