Drug screening

Longlong Si, Haiqing Bai, Melissa Rodas, et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature Biomedical Engineering. 2021;5(8):815-829. doi:10.1038/s41551-021-00718-9

Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, et al. Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review. Scientific Reports. 2021;11(1):6403. doi:10.1038/s41598-021-85708-2

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880

Andrew C. Daly, Matthew D. Davidson, Jason A. Burdick. 3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels. Nature Communications. 2021;12(1):753. doi:10.1038/s41467-021-21029-2

Ehsanollah Moradi, Sasan Jalili-Firoozinezhad, Mehran Solati-Hashjin. Microfluidic organ-on-a-chip models of human liver tissue. Acta Biomaterialia. 2020;116:67-83. doi:10.1016/j.actbio.2020.08.041

Abinaya R, Kavitha Govarthanan, Lakshmi Krishnan, et al. A Biomimetic Microfluidic Triple-compartment Periodontium-on-chip for Investigation of Inflammatory Responses in Periodontitis. Small. n/a(n/a):e73973. doi:10.1002/smll.73973

Surjendu Maity, Tamanna Bhuyan, Christopher Jewell, et al. Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications. Small. n/a(n/a):2405511. doi:10.1002/smll.202405511

Zhengyu Zou, Zhun Lin, Chenglin Wu, et al. Micro-Engineered Organoid-on-a-Chip Based on Mesenchymal Stromal Cells to Predict Immunotherapy Responses of HCC Patients. Advanced Science. n/a(n/a):2302640. doi:10.1002/advs.202302640