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George M. Gibbons, Tanja Fuchsberger, Mai Abdelgawad, et al. A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth. Cell Reports. 2026;45(6). doi:10.1016/j.celrep.2026.117399
Drug screening
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Qiong Chen, Jing Wang, Wenzhao Li, Luoran Shang, Dexuan Wang, Ping Duan. Drug Screening of Primary Human Endometriotic Cells Based on Micro-Encapsulating Microfluidic Chip. Advanced Science. 2025;12(20):2504647. doi:10.1002/advs.202504647
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Yufei Wang, Limin Zhang, Louis Zizhao Wang, et al. The application of organoids in treatment decision-making for digestive system cancers: progress and challenges. Molecular Cancer. 2025;24(1):222. doi:10.1186/s12943-025-02429-0
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Daisong Wang, Remi Villenave, Nadine Stokar-Regenscheit, Hans Clevers. Human organoids as 3D in vitro platforms for drug discovery: opportunities and challenges. Nature Reviews Drug Discovery. 2025:1-23. doi:10.1038/s41573-025-01317-y
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Daisong Wang, Remi Villenave, Nadine Stokar-Regenscheit, Hans Clevers. Human organoids as 3D in vitro platforms for drug discovery: opportunities and challenges. Nature Reviews Drug Discovery. 2025:1-23. doi:10.1038/s41573-025-01317-y
1.
Bettina Lickiss, Jan Hunker, Jamie Bhagwan, et al. Chamber-specific contractile responses of atrial and ventricular hiPSC-cardiomyocytes to GPCR and ion channel targeting compounds: A microphysiological system for cardiac drug development. Journal of Pharmacological and Toxicological Methods. 2024;128:107529. doi:10.1016/j.vascn.2024.107529
1.
Souradeep Dey, Amritha Bhat, G. Janani, Vartik Shandilya, Raghvendra Gupta, Biman B. Mandal. Microfluidic human physiomimetic liver model as a screening platform for drug induced liver injury. Biomaterials. 2024;310:122627. doi:10.1016/j.biomaterials.2024.122627
1.
Benjamin J. Dwyer, Janina E. E. Tirnitz-Parker. Patient-derived organoid models to decode liver pathophysiology. Trends in Endocrinology & Metabolism. 2024. doi:10.1016/j.tem.2024.07.019
1.
Anastasia Brooks, Yali Zhang, Jiezhong Chen, Chun-Xia Zhao. Cancer Metastasis-on-a-Chip for Modeling Metastatic Cascade and Drug Screening. Advanced Healthcare Materials. 2024;13(21):2302436. doi:10.1002/adhm.202302436
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Zhen Fang, Peijuan Li, Fengying Du, Liang Shang, Leping Li. The role of organoids in cancer research. Experimental Hematology & Oncology. 2023;12(1):69. doi:10.1186/s40164-023-00433-y