Animals

Cathalijn H. C. Leenaars, Carien Kouwenaar, Frans R. Stafleu, et al. Animal to human translation: a systematic scoping review of reported concordance rates. Journal of Translational Medicine. 2019;17(1):223. doi:10.1186/s12967-019-1976-2

Jarrod Bailey, Michael Balls. Recent efforts to elucidate the scientific validity of animal-based drug tests by the pharmaceutical industry, pro-testing lobby groups, and animal welfare organisations. BMC Medical Ethics. 2019;20(1):16. doi:10.1186/s12910-019-0352-3

Alessandro Polini, Loretta L. Del Mercato, Adriano Barra, Yu Shrike Zhang, Franco Calabi, Giuseppe Gigli. Towards the development of human immune-system-on-a-chip platforms. Drug Discovery Today. 2019;24(2):517-525. doi:10.1016/j.drudis.2018.10.003

Norman Sachs, Angelos Papaspyropoulos, Domenique D. Zomer-van Ommen, et al. Long-term expanding human airway organoids for disease modeling. The EMBO journal. 2019;38(4):e100300. doi:10.15252/embj.2018100300

Janet Piñero, Laura I. Furlong, Ferran Sanz. In silico models in drug development: where we are. Current Opinion in Pharmacology. 2018;42:111-121. doi:10.1016/j.coph.2018.08.007

Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041

Pandora Pound, Merel Ritskes-Hoitinga. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. Journal of Translational Medicine. 2018;16(1):304. doi:10.1186/s12967-018-1678-1

F. Claire Hankenson, James O. Marx, Christopher J. Gordon, John M. David. Effects of Rodent Thermoregulation on Animal Models in the Research Environment. Comparative Medicine. 2018;68(6):425-438. doi:10.30802/AALAS-CM-18-000049

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010

James T. Neal, Xingnan Li, Junjie Zhu, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175(7):1972-1988.e16. doi:10.1016/j.cell.2018.11.021