Animals

Sabrina Ehnert, Helen Rinderknecht, Romina H. Aspera-Werz, Victor Häussling, Andreas K. Nussler. Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models. Archives of Toxicology. 2020;94(12):3937-3958. doi:10.1007/s00204-020-02906-z

Fjodor A. Yousef Yengej, Jitske Jansen, Maarten B. Rookmaaker, Marianne C. Verhaar, Hans Clevers. Kidney Organoids and Tubuloids. Cells. 2020;9(6):1326. doi:10.3390/cells9061326

Jie Zhou, Cun Li, Xiaojuan Liu, et al. Infection of bat and human intestinal organoids by SARS-CoV-2. Nature Medicine. 2020;26(7):1077-1083. doi:10.1038/s41591-020-0912-6

Laura Pellegrini, Anna Albecka, Donna L. Mallery, et al. SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids. Cell Stem Cell. 2020;27(6):951-961.e5. doi:10.1016/j.stem.2020.10.001

Huaqi Tang, Yasmine Abouleila, Longlong Si, et al. Human Organs-on-Chips for Virology. Trends in Microbiology. 2020;28(11):934-946. doi:10.1016/j.tim.2020.06.005

Vanessa Monteil, Hyesoo Kwon, Patricia Prado, et al. Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2. Cell. 2020;181(4):905-913.e7. doi:10.1016/j.cell.2020.04.004

Yesl Jun, JaeSeo Lee, Seongkyun Choi, et al. In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids. Science Advances. 2019;5(11):eaax4520. doi:10.1126/sciadv.aax4520

Michael Balls, Jarrod Bailey, Robert D. Combes. How viable are alternatives to animal testing in determining the toxicities of therapeutic drugs? Expert Opinion on Drug Metabolism & Toxicology. 2019;15(12):985-987. doi:10.1080/17425255.2019.1694662

Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens. Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research. Alternatives to Animal Experimentation. 2019;36(3):343-352. doi:10.14573/altex.1907031

Sabina Kanton, Michael James Boyle, Zhisong He, et al. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature. 2019;574(7778):418-422. doi:10.1038/s41586-019-1654-9