Respiratory system

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Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, et al. A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient-Derived Fibroblasts Impair Angiogenesis and Vasculogenesis. Advanced Functional Materials. 2026;36(28):e15610. doi:10.1002/adfm.202515610
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Henriette H. M. Dreyer, Georgia-Nefeli Ithakisiou, Sacha Spelier, et al. Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modeling. Cell Reports Medicine. 2026. doi:10.1016/j.xcrm.2026.102692
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Zhuowei Gong, Dhruv Bhattaram, Laura Porritt, et al. Recapitulating apicobasal tissue polarity in extracellular matrix-incorporated airway organoids. Biomaterials. 2026;331:124084. doi:10.1016/j.biomaterials.2026.124084
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Lin Lin, Carla Pou Casellas, Antonella F. M. Dost, et al. Human airway submucosal gland organoids to study respiratory inflammation and infection. Cell Stem Cell. 2025;32(7):1170-1182.e7. doi:10.1016/j.stem.2025.05.013
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Hae-Ran Park, Yeongkag Kwon, Hyun Jung Ji, et al. A human lung organoid platform for studying radiation-induced pulmonary fibrosis and antifibrotic drug screening. Scientific Reports. 2025. doi:10.1038/s41598-025-31582-1
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Robert M. Geiger, Shekh M. Rahman, Md Shadiqur Rashid Roni, et al. Assessment of drug permeability using a small airway microphysiological system. Frontiers in Pharmacology. 2025;16. doi:10.3389/fphar.2025.1621775
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Akina Mori, Marjolein Vermeer, Lenie J. van den Broek, et al. High-throughput Bronchus-on-a-Chip system for modeling the human bronchus. Scientific Reports. 2024;14(1):26248. doi:10.1038/s41598-024-77665-3
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Rahaf Issa, Neus Lozano, Kostas Kostarelos, Sandra Vranic. Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures. Nano Today. 2024;56:102254. doi:10.1016/j.nantod.2024.102254
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Michelle Brand, Felix Ritzmann, Kathrin Kattler, et al. Biochemical and transcriptomic evaluation of a 3D lung organoid platform for pre-clinical testing of active substances targeting senescence. Respiratory Research. 2024;25:3. doi:10.1186/s12931-023-02636-7
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Avishekh Gautam, David F. Boyd, Sameer Nikhar, et al. Necroptosis blockade prevents lung injury in severe influenza. Nature. 2024;628(8009):835-843. doi:10.1038/s41586-024-07265-8
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