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Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modeling

Henriette H. M. Dreyer, Georgia-Nefeli Ithakisiou, Sacha Spelier, Malina K. Iwanski, Eugene Katrukha, Jonne Terstappen, Lisa W. Rodenburg, Aditi Shekhar, Loes A. den Hertog-Oosterhoff, Shannon M. A. Smits, Isabelle S. van der Windt, Lotte T. Azink, Linda H. M. Bijlard, Koen Passier, Sam F. B. van Beuningen, Robert Jan Lebbink, Eric G. Haarman, Cornelis K. van der Ent, Lukas C. Kapitein, Louis J. Bont, Jeffrey M. Beekman, Gimano D. Amatngalim
Cell Reports Medicine. 2026. doi: 10.1016/j.xcrm.2026.102692
https://www.cell.com/cell-reports-medicine/abstract/S2666-3791(26)00109-6
Keywords
RSV
airway epithelial cell cultures
airway organoids
Cystic Fibrosis
high-throughput epithelial screening
mucociliary epithelium
nasal epithelial cells
patient-derived airway epithelial models
primary ciliary dyskinesia
respiratory syncytial virus
submerged differentiation
Library Collection(s)
Respiratory system
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The content of this website is adapted from Krebs et al., Author Guide for Addressing Animal Methods Bias in Publishing. Advanced Science. 2023 Aug 30:e2303226. doi: 10.1002/advs.202303226. © 2023 by Krebs et al. is licensed under CC BY 4.0. Advanced Science, published by Wiley-VCH GmbH. Wiley-VCH GmbH does not endorse the COLAAB, nor our use of the content. 

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