Nervous system

Kyubin Seo, Subin Cho, Hyogeun Shin, et al. Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord-Like Organoid (pSCO) with Dorsoventral Organization. Advanced Science. 2023;10(20):2301787. doi:10.1002/advs.202301787

János M. Réthelyi, Katalin Vincze, Dorothea Schall, Jeffrey Glennon, Simone Berkel. The role of insulin/IGF1 signalling in neurodevelopmental and neuropsychiatric disorders – Evidence from human neuronal cell models. Neuroscience & Biobehavioral Reviews. 2023;153:105330. doi:10.1016/j.neubiorev.2023.105330

Ayşe J. Muñiz, Tuğba Topal, Michael D. Brooks, et al. Engineered extracellular matrices facilitate brain organoids from human pluripotent stem cells. Annals of Clinical and Translational Neurology. 2023;10(7):1239-1253. doi:10.1002/acn3.51820

Yogita K. Adlakha. Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. Cell Death Discovery. 2023;9(1):1-17. doi:10.1038/s41420-023-01523-w

Rebecca Sebastian, Kang Jin, Narciso Pavon, et al. Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids. Nature Communications. 2023;14(1):3770. doi:10.1038/s41467-023-39420-6

Michel H. Y. Hu, Jean-Philippe Frimat, Kim Rijkers, et al. Spontaneous Epileptic Recordings from hiPSC-Derived Cortical Neurons Cultured with a Human Epileptic Brain Biopsy on a Multi Electrode Array. Applied Sciences. 2023;13(3):1432. doi:10.3390/app13031432

Jacqueline A. Tickle, Jon Sen, Christopher Adams, et al. A benchtop brain injury model using resected donor tissue from patients with Chiari malformation. Neural Regeneration Research. 2023;18(5):1057. doi:10.4103/1673-5374.355761

Paula Barreras, David Pamies, Thomas Hartung, Carlos A. Pardo. Human brain microphysiological systems in the study of neuroinfectious disorders. Experimental Neurology. 2023;365:114409. doi:10.1016/j.expneurol.2023.114409

Nicolas Daviaud, Eric Chen, Tara Edwards, Saud A. Sadiq. Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect. Biology Open. 2023;12(3):bio059845. doi:10.1242/bio.059845

Lu Wang, Charlotte Owusu-Hammond, David Sievert, Joseph G. Gleeson. Stem Cell–Based Organoid Models of Neurodevelopmental Disorders. Biological Psychiatry. 2023;93(7):622-631. doi:10.1016/j.biopsych.2023.01.012